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Literature DB >> 8406894

Effect of orally administered monoclonal antibody on persistent Cryptosporidium parvum infection in scid mice.

Abstract

Scid mice, persistently infected after exposure to 10(7) Cryptosporidium parvum oocysts, were treated daily for 14 to 17 days with 0.4 mg of monoclonal antibody (mAb) 17.41 administered by the oral route. Mice receiving mAb 17.41 shed significantly fewer (P < 0.005) C. parvum oocysts than scid mice receiving isotype control mAb. Intestinal (but not gastric) infectivity scores were also reduced for scid mice treated with mAb 17.41 (P < 0.01).

Entities: Disease Species

Mesh：

Substances：
Antibodies, Monoclonal

Year: 1993 PMID： 8406894 PMCID： PMC281254 DOI： 10.1128/iai.61.11.4906-4908.1993

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

24 in total

1. Isolated antral narrowing associated with gastrointestinal cryptosporidiosis in acquired immunodeficiency syndrome.

Authors: E Cersosimo; C J Wilkowske; J E Rosenblatt; J Ludwig
Journal: Mayo Clin Proc Date: 1992-06 Impact factor: 7.616

2. Cryptosporidiosis in adult and neonatal mice with severe combined immunodeficiency.

Authors: T L Kuhls; R A Greenfield; D A Mosier; D L Crawford; W A Joyce
Journal: J Comp Pathol Date: 1992-05 Impact factor: 1.311

Review 3. Cryptosporidium species, a protean protozoan.

Authors: E N Janoff; L B Reller
Journal: J Clin Microbiol Date: 1987-06 Impact factor: 5.948

Review 4. Cryptosporidium spp. and cryptosporidiosis.

Authors: R Fayer; B L Ungar
Journal: Microbiol Rev Date: 1986-12

Review 5. Cryptosporidiosis: clinical, epidemiologic, and parasitologic review.

Authors: T R Navin; D D Juranek
Journal: Rev Infect Dis Date: 1984 May-Jun

Review 6. Cryptosporidium and cryptosporidiosis.

Authors: R Soave; D Armstrong
Journal: Rev Infect Dis Date: 1986 Nov-Dec

7. Human cryptosporidiosis in the acquired immune deficiency syndrome.

Authors: L A Guarda; S A Stein; K A Cleary; N G Ordóñez
Journal: Arch Pathol Lab Med Date: 1983-11 Impact factor: 5.534

8. Human cryptosporidiosis in immunocompetent and immunodeficient persons. Studies of an outbreak and experimental transmission.

Authors: W L Current; N C Reese; J V Ernst; W S Bailey; M B Heyman; W M Weinstein
Journal: N Engl J Med Date: 1983-05-26 Impact factor: 91.245

9. Cryptosporidiosis of the stomach and small intestine in patients with AIDS.

Authors: R N Berk; S D Wall; C B McArdle; J A McCutchan; A R Clemett; J S Rosenblum; A Premkumer; A J Megibow
Journal: AJR Am J Roentgenol Date: 1984-09 Impact factor: 3.959

Review 10. Autopsy pathology in the acquired immune deficiency syndrome.

Authors: C M Reichert; T J O'Leary; D L Levens; C R Simrell; A M Macher
Journal: Am J Pathol Date: 1983-09 Impact factor: 4.307

11 in total

1. Enteral human serum immunoglobulin treatment of cryptosporidiosis in mice with severe combined immunodeficiency.

Authors: T L Kuhls; S L Orlicek; D A Mosier; D L Crawford; V L Abrams; R A Greenfield
Journal: Infect Immun Date: 1995-09 Impact factor: 3.441

Review 2. SCID mice and the study of parasitic disease.

Authors: K B Seydel; S L Stanley
Journal: Clin Microbiol Rev Date: 1996-04 Impact factor: 26.132

3. Cloning and sequence analysis of a highly polymorphic Cryptosporidium parvum gene encoding a 60-kilodalton glycoprotein and characterization of its 15- and 45-kilodalton zoite surface antigen products.

Authors: W B Strong; J Gut; R G Nelson
Journal: Infect Immun Date: 2000-07 Impact factor: 3.441

4. Efficacy of monoclonal antibodies against defined antigens for passive immunotherapy of chronic gastrointestinal cryptosporidiosis.

Authors: Michael W Riggs; Deborah A Schaefer; Sushila J Kapil; Lise Barley-Maloney; Lance E Perryman
Journal: Antimicrob Agents Chemother Date: 2002-02 Impact factor: 5.191

5. In vitro inhibition of Cryptosporidium parvum infection by human monoclonal antibodies.

Authors: B C Elliot; A V Wisnewski; J Johnson; D Fenwick-Smith; P Wiest; D Hamer; T Kresina; T P Flanigan
Journal: Infect Immun Date: 1997-09 Impact factor: 3.441

6. Comparison of Cryptosporidium parvum and Cryptosporidium wrairi by reactivity with monoclonal antibodies and ability to infect severe combined immunodeficient mice.

Authors: C E Chrisp; P Mason; L E Perryman
Journal: Infect Immun Date: 1995-01 Impact factor: 3.441