Literature DB >> 8406843

Monocyte antimycobacterial activity before and after Mycobacterium bovis BCG vaccination in Chingleput, India, and London, United Kingdom.

S H Cheng1, K B Walker, D B Lowrie, D A Mitchison, R Swamy, M Datta, R Prabhakar.   

Abstract

Monocytes from purified protein derivative S Mantoux-negative children and young adults inhibited intracellular growth of Mycobacterium microti more in Chingleput than in London. Mycobacterium bovis BCG vaccination did not enhance bacteriostasis with the Indians but did so with the Londoners. No evidence was found for involvement of cytokines such as macrophage-activating factor and granulocyte macrophage colony-stimulating factor in the differences.

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Year:  1993        PMID： 8406843      PMCID： PMC281188          DOI： 10.1128/iai.61.10.4501-4503.1993

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


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