Literature DB >> 8406838

The RESA-2 gene of Plasmodium falciparum is transcribed in several independent isolates.

G Vazeux1, C Le Scanf, T Fandeur.   

Abstract

The relevance of the ring-infected erythrocyte surface antigen (RESA) of Plasmodium falciparum as a malaria vaccine candidate has been questioned of late because RESA-deficient parasites have been found to multiply normally in culture or in monkeys. The RESA-2 gene was recently described as a pseudogene highly homologous to RESA. In this report, we demonstrate that RESA-2 is not a pseudogene, because we were able to detect RESA-2 transcripts in asexual blood stages of multiple isolates by using polymerase chain reaction on reverse-transcribed mRNA. Transcription of RESA-2 was observed whether or not the isolates studied expressed the RESA protein.

Entities:  

Mesh：

Substances：

Year:  1993        PMID： 8406838      PMCID： PMC281181          DOI： 10.1128/iai.61.10.4469-4472.1993

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  17 in total

1.  Cloning and analysis of the RESA-2 gene: a DNA homologue of the ring-infected erythrocyte surface antigen gene of Plasmodium falciparum.

Authors:  R Cappai; D C Kaslow; M G Peterson; A F Cowman; R F Anders; D J Kemp
Journal:  Mol Biochem Parasitol       Date:  1992-09       Impact factor: 1.759

2.  A and T homopolymeric stretches mediate a DNA inversion in Plasmodium falciparum which results in loss of gene expression.

Authors:  L G Pologe; D de Bruin; J V Ravetch
Journal:  Mol Cell Biol       Date:  1990-06       Impact factor: 4.272

3.  Passive immunization of Aotus monkeys with human antibodies to the Plasmodium falciparum antigen Pf155/RESA.

Authors:  K Berzins; H Perlmann; B Wåhlin; H P Ekre; B Högh; E Petersen; B Wellde; M Schoenbechler; J Williams; J Chulay
Journal:  Infect Immun       Date:  1991-04       Impact factor: 3.441

4.  Homologous genes encode two distinct histidine-rich proteins in a cloned isolate of Plasmodium falciparum.

Authors:  T E Wellems; R J Howard
Journal:  Proc Natl Acad Sci U S A       Date:  1986-08       Impact factor: 11.205

5.  Immune sera recognize on erythrocytes Plasmodium falciparum antigen composed of repeated amino acid sequences.

Authors:  R L Coppel; A F Cowman; R F Anders; A E Bianco; R B Saint; K R Lingelbach; D J Kemp; G V Brown
Journal:  Nature       Date:  1984 Aug 30-Sep 5       Impact factor: 49.962

6.  The ring-infected erythrocyte surface antigen (RESA) polypeptide of Plasmodium falciparum contains two separate blocks of tandem repeats encoding antigenic epitopes that are naturally immunogenic in man.

Authors:  A F Cowman; R L Coppel; R B Saint; J Favaloro; P E Crewther; H D Stahl; A E Bianco; G V Brown; R F Anders; D J Kemp
Journal:  Mol Biol Med       Date:  1984-06

7.  A Plasmodium falciparum blood stage antigen highly homologous to the glycophorin binding protein GBP.

Authors:  D Nolte; E Hundt; G Langsley; B Knapp
Journal:  Mol Biochem Parasitol       Date:  1991-12       Impact factor: 1.759

8.  In vivo and in vitro derived Palo Alto lines of Plasmodium falciparum are genetically unrelated.

Authors:  T Fandeur; S Bonnefoy; O Mercereau-Puijalon
Journal:  Mol Biochem Parasitol       Date:  1991-08       Impact factor: 1.759

9.  The ring-infected erythrocyte surface antigen of Plasmodium falciparum associates with spectrin in the erythrocyte membrane.

Authors:  M Foley; L Tilley; W H Sawyer; R F Anders
Journal:  Mol Biochem Parasitol       Date:  1991-05       Impact factor: 1.759

10.  Protection of squirrel monkeys against virulent Plasmodium falciparum infections by use of attenuated parasites.

Authors:  T Fandeur; J Gysin; O Mercereau-Puijalon
Journal:  Infect Immun       Date:  1992-04       Impact factor: 3.441
View more
  11 in total

1.  Novel target antigens of the variant-specific immune response to Plasmodium falciparum identified by differential screening of an expression library.

Authors:  C Le Scanf; T Fandeur; S Bonnefoy; M Guillotte; O Mercereau-Puijalon
Journal:  Infect Immun       Date:  1999-01       Impact factor: 3.441

2.  Genes coding for tryptophan-rich proteins are transcribed throughout the asexual cycle of Plasmodium falciparum.

Authors:  Francis B Ntumngia; Noemi Bahamontes-Rosa; Jürgen F J Kun
Journal:  Parasitol Res       Date:  2005-05-28       Impact factor: 2.289

3.  Possible relationship between Plasmodium falciparum ring-infected erythrocyte surface antigen (RESA) and host cell resistance to destruction by chemicals.

Authors:  Augustine U Orjih; Preethi T Cherian
Journal:  Parasitol Res       Date:  2013-09-05       Impact factor: 2.289

4.  Antibodies to a non-repeat region of Plasmodium falciparum antigen Pf155/RESA in individuals from malaria-endemic areas.

Authors:  A B Siddique; N Ahlborg; M Warsame; P Perlmann; K Berzins
Journal:  Clin Exp Immunol       Date:  1999-06       Impact factor: 4.330

5.  In vivo transcriptome of Plasmodium falciparum reveals overexpression of transcripts that encode surface proteins.

Authors:  Johanna P Daily; Karine G Le Roch; Ousmane Sarr; Daouda Ndiaye; Amanda Lukens; Yingyao Zhou; Omar Ndir; Soulyemane Mboup; Ali Sultan; Elizabeth A Winzeler; Dyann F Wirth
Journal:  J Infect Dis       Date:  2005-02-28       Impact factor: 5.226

Review 6.  Malaria parasite proteins that remodel the host erythrocyte.

Authors:  Alexander G Maier; Brian M Cooke; Alan F Cowman; Leann Tilley
Journal:  Nat Rev Microbiol       Date:  2009-05       Impact factor: 60.633

7.  Possible association of the Plasmodium falciparum T1526C resa2 gene mutation with severe malaria.

Authors:  Rémy Durand; Florence Migot-Nabias; Valérie Andriantsoanirina; Elise Seringe; Firmine Viwami; Gratien Sagbo; Francis Lalya; Philippe Deloron; Odile Mercereau-Puijalon; Serge Bonnefoy
Journal:  Malar J       Date:  2012-04-25       Impact factor: 2.979

8.  Immunoglobulin response to Plasmodium falciparum RESA proteins in uncomplicated and severe malaria.

Authors:  Cyril Badaut; Léa Guyonnet; Jacqueline Milet; Emmanuelle Renard; Rémy Durand; Firmine Viwami; Gratien Sagbo; Francis Layla; Philippe Deloron; Serge Bonnefoy; Florence Migot-Nabias
Journal:  Malar J       Date:  2015-07-16       Impact factor: 2.979

9.  Immune pressure selects for Plasmodium falciparum parasites presenting distinct red blood cell surface antigens and inducing strain-specific protection in Saimiri sciureus monkeys.

Authors:  T Fandeur; C Le Scanf; B Bonnemains; C Slomianny; O Mercereau-Puijalon
Journal:  J Exp Med       Date:  1995-01-01       Impact factor: 14.307

10.  Genome-wide regulatory dynamics of translation in the Plasmodium falciparum asexual blood stages.

Authors:  Florence Caro; Vida Ahyong; Miguel Betegon; Joseph L DeRisi
Journal:  Elife       Date:  2014-12-10       Impact factor: 8.140
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.