Literature DB >> 8406601

Anti-platelet activating factor property of Rubia cordifolia Linn.

Y B Tripathi1, S Pandey, S D Shukla.   

Abstract

Rubia cordifolia is clinically used for the purification of blood by the physicians of the Indian System of Medicine. For the first time, the effect of the partially purified fraction of this whole plant has been studied on rabbit platelets. It inhibits the platelet aggregation induced by PAF (platelet activating factor) but not thrombin. It also inhibits the binding of 3H-PAF to the platelets in the dose-dependent manner. Thus it appears that R. cordifolia inhibits action of PAF at its receptor level either by it's blocking or by desensitization.

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Year:  1993        PMID： 8406601

Source DB:  PubMed          Journal:  Indian J Exp Biol        ISSN： 0019-5189            Impact factor:   0.818


  3 in total

1.  Anti-diarrheal and anti-inflammatory activities of aqueous extract of the aerial part of Rubia cordifolia.

Authors:  Xue-Peng Gong; Yuan-Yuan Sun; Wei Chen; Xia Guo; Jian-Kun Guan; Dong-Yan Li; Guang Du
Journal:  BMC Complement Altern Med       Date:  2017-01-05       Impact factor: 3.659

Review 2.  A comprehensive review of Rubia cordifolia L.: Traditional uses, phytochemistry, pharmacological activities, and clinical applications.

Authors:  Min Wen; Qi Chen; Wang Chen; Jing Yang; Xiaogang Zhou; Chunxiang Zhang; Anguo Wu; Jia Lai; Jianping Chen; Qibing Mei; Shuo Yang; Cai Lan; Jianming Wu; Feihong Huang; Long Wang
Journal:  Front Pharmacol       Date:  2022-09-09       Impact factor: 5.988

3.  Characterization of Rubia cordifolia L. root extract and its evaluation of cardioprotective effect in Wistar rat model.

Authors:  B S Chandrashekar; S Prabhakara; T Mohan; D Shabeer; Basavaraj Bhandare; M Nalini; P S Sharmila; D L Meghana; Basanth Kumar Reddy; H M Hanumantha Rao; H Sahajananda; K Anbazhagan
Journal:  Indian J Pharmacol       Date:  2018 Jan-Feb       Impact factor: 1.200
  3 in total

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