Literature DB >> 8405386

Biosynthesis of vitamin B12. Discovery of the enzymes for oxidative ring contraction and insertion of the fourth methyl group.

A I Scott1, C A Roessner, N J Stolowich, J B Spencer, C Min, S I Ozaki.   

Abstract

In the vitamin B12 biosynthetic pathway the enzymes responsible for the conversion of precorrin-3 to precorrin-4 have been identified as the gene products of cobG and cobJ from Pseudomonas denitrificans. CobG catalyzes the oxidation of precorrin-3 to precorrin-3x (a hydroxy lactone) whereas CobJ is a SAM-dependent C-17 methyl transferase and is necessary for ring contraction. A mechanism for ring contraction is proposed.

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Year:  1993        PMID： 8405386     DOI： 10.1016/0014-5793(93)80306-f

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  9 in total

Review 1.  Algae need their vitamins.

Authors:  Martin T Croft; Martin J Warren; Alison G Smith
Journal:  Eukaryot Cell       Date:  2006-08

Review 2.  Fine-tuning our knowledge of the anaerobic route to cobalamin (vitamin B12).

Authors:  Charles A Roessner; A Ian Scott
Journal:  J Bacteriol       Date:  2006-08-25       Impact factor: 3.490

3.  Anaerobic growth of Paracoccus denitrificans requires cobalamin: characterization of cobK and cobJ genes.

Authors:  N Shearer; A P Hinsley; R J Van Spanning; S Spiro
Journal:  J Bacteriol       Date:  1999-11       Impact factor: 3.490

Review 4.  Methylthioadenosine/S-adenosylhomocysteine nucleosidase, a critical enzyme for bacterial metabolism.

Authors:  Nikhat Parveen; Kenneth A Cornell
Journal:  Mol Microbiol       Date:  2010-11-18       Impact factor: 3.501

5.  In vivo analysis of cobinamide salvaging in Rhodobacter sphaeroides strain 2.4.1.

Authors:  Michael J Gray; Jorge C Escalante-Semerena
Journal:  J Bacteriol       Date:  2009-04-17       Impact factor: 3.490

6.  Salmonella typhimurium cobalamin (vitamin B12) biosynthetic genes: functional studies in S. typhimurium and Escherichia coli.

Authors:  E Raux; A Lanois; F Levillayer; M J Warren; E Brody; A Rambach; C Thermes
Journal:  J Bacteriol       Date:  1996-02       Impact factor: 3.490

7.  Characterization of the enzyme CbiH60 involved in anaerobic ring contraction of the cobalamin (vitamin B12) biosynthetic pathway.

Authors:  Simon J Moore; Rebekka Biedendieck; Andrew D Lawrence; Evelyne Deery; Mark J Howard; Stephen E J Rigby; Martin J Warren
Journal:  J Biol Chem       Date:  2012-11-15       Impact factor: 5.157

8.  An enzyme-trap approach allows isolation of intermediates in cobalamin biosynthesis.

Authors:  Evelyne Deery; Susanne Schroeder; Andrew D Lawrence; Samantha L Taylor; Arefeh Seyedarabi; Jitka Waterman; Keith S Wilson; David Brown; Michael A Geeves; Mark J Howard; Richard W Pickersgill; Martin J Warren
Journal:  Nat Chem Biol       Date:  2012-10-07       Impact factor: 15.040

Review 9.  Biosynthesis of the modified tetrapyrroles-the pigments of life.

Authors:  Donald A Bryant; C Neil Hunter; Martin J Warren
Journal:  J Biol Chem       Date:  2020-04-02       Impact factor: 5.157
  9 in total

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