| Literature DB >> 8405303 |
T Aoki1, K Nihonyanagi, T Oba.
Abstract
Exposure of voltage-clamped frog skeletal muscle fibres to silver caused a maintained inward current which could be carried by Ca2+, Mg2+ or Na+. Inorganic Ca2+ channel blockers and dithiothreitol (SH reducing agent) diminished this current, but a Na+ channel blocker did not. Thus, silver activates the Ca2+ channel by acting on SH groups in a Ca2+ channel protein.Entities:
Mesh:
Substances:
Year: 1993 PMID: 8405303 DOI: 10.1007/bf01923550
Source DB: PubMed Journal: Experientia ISSN: 0014-4754