OBJECTIVE: To assess in diabetic subjects the effects of dietary sucrose on glycemia and lipemia. RESEARCH DESIGN AND METHODS: Twelve type II diabetic subjects consumed, in random order, two isocaloric, 55% carbohydrate study diets for 28 days. In one diet, 19% of energy was derived from sucrose. In the other diet, < 3% of energy was derived from sucrose, and carbohydrate energy came primarily from starch. Both study diets were composed of common foods. All meals were prepared in a metabolic kitchen where foods were weighed during meal preparation. RESULTS: No significant differences were noted between the study diets at any time point in mean plasma glucose. At day 28, mean plasma glucose values for the sucrose diet were 9.6 +/- 0.5 mM and for the starch diet were 9.4 +/- 0.6 mM (P = 0.63). Also, no significant differences were observed between the study diets in urine glucose, fasting serum total, HDL, or LDL cholesterol; fasting serum TG; or peak postprandial serum TG. CONCLUSIONS: A high sucrose diet did not adversely affect glycemia or lipemia in type II diabetic subjects.
RCT Entities:
OBJECTIVE: To assess in diabetic subjects the effects of dietary sucrose on glycemia and lipemia. RESEARCH DESIGN AND METHODS: Twelve type II diabetic subjects consumed, in random order, two isocaloric, 55% carbohydrate study diets for 28 days. In one diet, 19% of energy was derived from sucrose. In the other diet, < 3% of energy was derived from sucrose, and carbohydrate energy came primarily from starch. Both study diets were composed of common foods. All meals were prepared in a metabolic kitchen where foods were weighed during meal preparation. RESULTS: No significant differences were noted between the study diets at any time point in mean plasma glucose. At day 28, mean plasma glucose values for the sucrose diet were 9.6 +/- 0.5 mM and for the starch diet were 9.4 +/- 0.6 mM (P = 0.63). Also, no significant differences were observed between the study diets in urine glucose, fasting serum total, HDL, or LDL cholesterol; fasting serum TG; or peak postprandial serum TG. CONCLUSIONS: A high sucrose diet did not adversely affect glycemia or lipemia in type II diabetic subjects.
Authors: Huicui Meng; Nirupa R Matthan; Susan K Fried; Silvia Berciano; Maura E Walker; Jean M Galluccio; Alice H Lichtenstein Journal: J Clin Endocrinol Metab Date: 2018-09-01 Impact factor: 5.958
Authors: Maren R Laughlin; John P Bantle; Peter J Havel; Elizabeth Parks; David M Klurfeld; Karen Teff; Padma Maruvada Journal: Adv Nutr Date: 2014-05-14 Impact factor: 8.701
Authors: Anna Rosiek; Natalia Frąckowiak Maciejewska; Krzysztof Leksowski; Aleksandra Rosiek-Kryszewska; Łukasz Leksowski Journal: Int J Environ Res Public Health Date: 2015-08-12 Impact factor: 3.390
Authors: Vivian L Choo; Effie Viguiliouk; Sonia Blanco Mejia; Adrian I Cozma; Tauseef A Khan; Vanessa Ha; Thomas M S Wolever; Lawrence A Leiter; Vladimir Vuksan; Cyril W C Kendall; Russell J de Souza; David J A Jenkins; John L Sievenpiper Journal: BMJ Date: 2018-11-21