Literature DB >> 8401413

Biosynthesis in vitro of 2-(3-amino-3-carboxypropyl)-isoxazolin-5-one, the neurotoxic amino acid in Lathyrus odoratus.

F Ikegami1, R Sakai, T Ishikawa, Y H Kuo, F Lambein, I Murakoshi.   

Abstract

2-(3-Amino-3-carboxypropyl)-isoxazolin-5-one (ACI), a neurotoxic amino acid from Lathyrus odoratus, was confirmed to be derived enzymatically from S-adenosyl-L-methionine (SAM) and isoxazolin-5-one. Some properties of an enzyme in the biosynthesis of ACI are described.

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Year:  1993        PMID： 8401413     DOI： 10.1248/bpb.16.732

Source DB:  PubMed          Journal:  Biol Pharm Bull        ISSN： 0918-6158            Impact factor:   2.233


  2 in total

Review 1.  S-Adenosylmethionine-dependent alkylation reactions: when are radical reactions used?

Authors:  Hening Lin
Journal:  Bioorg Chem       Date:  2011-06-28       Impact factor: 5.275

2.  Pyridoxal-5'-phosphate-dependent alkyl transfer in nucleoside antibiotic biosynthesis.

Authors:  Zheng Cui; Jonathan Overbay; Xiachang Wang; Xiaodong Liu; Yinan Zhang; Minakshi Bhardwaj; Anke Lemke; Daniel Wiegmann; Giuliana Niro; Jon S Thorson; Christian Ducho; Steven G Van Lanen
Journal:  Nat Chem Biol       Date:  2020-06-01       Impact factor: 15.040
  2 in total

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