Literature DB >> 8401359

Preparation for marrow transplantation in Hodgkin's and non-Hodgkin's lymphoma using Bu/CY.

B R Avalos1, J L Klein, N Kapoor, P J Tutschka, J P Klein, E A Copelan.   

Abstract

The results of autologous and allogeneic BMT in 44 patients with Hodgkin's or non-Hodgkin's lymphomas who received preparative therapy consisting of busulfan 16 mg/kg and cyclophosphamide 120 mg/kg are presented. Sixteen patients are surviving free of disease between 8 months and 6 years after transplantation. Thirteen patients either did not attain complete remission or experienced a recurrence of their disease. Fifteen patients died from treatment-related complications. Karnofsky score < or = 70, lactate dehydrogenase greater than twice normal and the development of hepatic veno-occlusive disease were associated with failure to achieve lymphoma-free survival.

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Year:  1993        PMID: 8401359

Source DB:  PubMed          Journal:  Bone Marrow Transplant        ISSN: 0268-3369            Impact factor:   5.483


  4 in total

Review 1.  Efficacy and toxicity of radiation in preparative regimens for pediatric stem cell transplantation. I: Clinical applications and therapeutic effects.

Authors:  T D Miale; S Sirithorn; S Ahmed
Journal:  Med Oncol       Date:  1995-12       Impact factor: 3.064

2.  Fixed-dose administration and pharmacokinetically guided adjustment of busulfan dose for patients undergoing hematopoietic stem cell transplantation: a meta-analysis and cost-effectiveness analysis.

Authors:  Tingting Chen; Chaoxin Chen; Xin He; Jianming Guo; Maobai Liu; Bin Zheng
Journal:  Ann Hematol       Date:  2022-01-29       Impact factor: 3.673

3.  Busulfan, etoposide, cytarabine, and melphalan as a high-dose regimen for autologous stem cell transplantation in peripheral T-cell lymphomas.

Authors:  Jae-Cheol Jo; Jin-Seok Kim; Je-Hwan Lee; Jung-Hee Lee; Seong Nam Im; Sang-Min Lee; Sung-Soo Yoon; In-Ho Kim; Seong Hwa Bae; Yoo Jin Lee; Yunsuk Choi; Won-Sik Lee
Journal:  Ann Hematol       Date:  2020-11-17       Impact factor: 3.673

4.  Dose-reduced busulfan, cyclophosphamide, and autologous stem cell transplantation for human immunodeficiency virus-associated lymphoma: AIDS Malignancy Consortium study 020.

Authors:  Thomas R Spitzer; Richard F Ambinder; Jeannette Y Lee; Lawrence D Kaplan; William Wachsman; David J Straus; David M Aboulafia; David T Scadden
Journal:  Biol Blood Marrow Transplant       Date:  2008-01       Impact factor: 5.742

  4 in total

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