Literature DB >> 8400612

Spurious dual-energy X-ray absorptiometry images in a patient exposed to the contrast agent Thorotrast.

D Stern1, R Zamenhof, B Dawson-Hughes.   

Abstract

A 69-year-old woman presented with a 20-year history of back pain and a 10 cm height loss. She had received an injection of the contrast agent, Thorotrast, at age 23. There was no history of fluoride exposure. Multiple vertebral compression fractures were seen on radiographs. Dual-energy X-ray absorptiometry (DXA) scans revealed high normal bone mineral content on the spine and, on whole body scan, visualization of the liver and spleen regions. Given the attenuation coefficient of thorium and the thorium concentrations reported for liver, spleen and vertebral bodies, it is likely that thorium was visualized in the liver and spleen and that it caused spurious elevation in her DXA bone mineral content values.

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Year:  1993        PMID: 8400612     DOI: 10.1007/bf01623834

Source DB:  PubMed          Journal:  Osteoporos Int        ISSN: 0937-941X            Impact factor:   4.507


  12 in total

1.  Late clinical changes following the internal deposition of radioactive materials.

Authors:  W B LOONEY
Journal:  Ann Intern Med       Date:  1955-02       Impact factor: 25.391

2.  History of the use and toxicity of thorotrast.

Authors:  J D Abbatt
Journal:  Environ Res       Date:  1979-02       Impact factor: 6.498

3.  Late clinical and roentgen observations following Thorotrast administration.

Authors:  B Gondos
Journal:  Clin Radiol       Date:  1973-04       Impact factor: 2.350

4.  Prediction of postmenopausal fracture risk with use of bone mineral measurements.

Authors:  R D Wasnich; P D Ross; L K Heilbrun; J M Vogel
Journal:  Am J Obstet Gynecol       Date:  1985-12-01       Impact factor: 8.661

5.  Ghost infantile vertebrae and hemipelves within adult skeleton from thorotrast administration in childhood.

Authors:  J G Teplick; G L Head; M E Kricun; M E Haskin
Journal:  Radiology       Date:  1978-12       Impact factor: 11.105

6.  Movement of thorotrast aggregates in the bone marrow.

Authors:  J da S Horta; J M Nunes
Journal:  Environ Res       Date:  1979-02       Impact factor: 6.498

Review 7.  Effects of Thorotrast in humans.

Authors:  B J Stover
Journal:  Health Phys       Date:  1983       Impact factor: 1.316

Review 8.  Thorotrast-associated sarcoma of bone: A case report and review of the literature.

Authors:  T J Harrist; A L Schiller; R L Trelstad; H J Mankin; C W Mays
Journal:  Cancer       Date:  1979-12       Impact factor: 6.860

9.  Axial and appendicular bone density predict fractures in older women.

Authors:  D M Black; S R Cummings; H K Genant; M C Nevitt; L Palermo; W Browner
Journal:  J Bone Miner Res       Date:  1992-06       Impact factor: 6.741

10.  Age and bone mass as predictors of fracture in a prospective study.

Authors:  S L Hui; C W Slemenda; C C Johnston
Journal:  J Clin Invest       Date:  1988-06       Impact factor: 14.808

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