Literature DB >> 8400322

Epidermal growth factor-like activity and epidermal growth factor-receptors in human primary breast cancer.

Z Kahán1, M Szücs, M Vecsernyés, S Eckhardt.   

Abstract

Ligands binding to epidermal growth factor-receptors (EGF-Rs) as epidermal growth factor-like activity (EGF-like activity), along with EGF-R levels, were determined from human primary breast cancer samples. Receptor analysis revealed a single class of high affinity binding sites. Ng/mg protein EGF-like activity quantities were measured in cytosols, and were inversely correlated with EGF-R contents (p < 0.01), estimated by two-point assays.

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Year:  1993        PMID: 8400322     DOI: 10.1007/bf00682698

Source DB:  PubMed          Journal:  Breast Cancer Res Treat        ISSN: 0167-6806            Impact factor:   4.872


  24 in total

1.  Preparation of iodine-131 labelled human growth hormone of high specific activity.

Authors:  W M HUNTER; F C GREENWOOD
Journal:  Nature       Date:  1962-05-05       Impact factor: 49.962

2.  Measurement of occupied and non-occupied epidermal growth factor receptor sites in 216 human breast cancer biopsies.

Authors:  N Falette; M F Lefebvre; F Meggouh; M Eynard; E Garin; S Saez
Journal:  Breast Cancer Res Treat       Date:  1992-03       Impact factor: 4.872

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Authors:  J E de Larco; G J Todaro
Journal:  Proc Natl Acad Sci U S A       Date:  1978-08       Impact factor: 11.205

4.  Receptor binding and processing of epidermal growth factor by human breast cancer cells.

Authors:  C K Osborene; B Hamilton; M Nover
Journal:  J Clin Endocrinol Metab       Date:  1982-07       Impact factor: 5.958

5.  8th San Antonio Breast Cancer Symposium--Plenary lecture. Autocrine and paracrine growth regulation of human breast cancer.

Authors:  M E Lippman; R B Dickson; S Bates; C Knabbe; K Huff; S Swain; M McManaway; D Bronzert; A Kasid; E P Gelmann
Journal:  Breast Cancer Res Treat       Date:  1986       Impact factor: 4.872

6.  Evidence for the involvement of the submandibular gland epidermal growth factor in mouse mammary tumorigenesis.

Authors:  H Kurachi; S Okamoto; T Oka
Journal:  Proc Natl Acad Sci U S A       Date:  1985-09       Impact factor: 11.205

7.  Immunological detection and quantitation of alpha transforming growth factors in human breast carcinoma cells.

Authors:  I Perroteau; D Salomon; M DeBortoli; W Kidwell; P Hazarika; R Pardue; J Dedman; J Tam
Journal:  Breast Cancer Res Treat       Date:  1986       Impact factor: 4.872

8.  Measurement of somatomedin-related peptides in fetal, neonatal, and maternal rat serum by insulin-like growth factor (IGF) I radioimmunoassay, IGF-II radioreceptor assay (RRA), and multiplication-stimulating activity RRA after acid-ethanol extraction.

Authors:  W H Daughaday; K A Parker; S Borowsky; B Trivedi; M Kapadia
Journal:  Endocrinology       Date:  1982-02       Impact factor: 4.736

9.  Epidermal growth factor and transforming growth factor alpha induce ascitic fluid in mice.

Authors:  E Ohmura; T Tsushima; Y Kamiya; M Okada; N Onoda; K Shizume; H Demura
Journal:  Cancer Res       Date:  1990-08-15       Impact factor: 12.701

10.  Quantitative assays of epidermal growth factor receptor in human breast cancer: cut-off points of clinical relevance.

Authors:  S Nicholson; J R Sainsbury; G K Needham; P Chambers; J R Farndon; A L Harris
Journal:  Int J Cancer       Date:  1988-07-15       Impact factor: 7.396

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  1 in total

Review 1.  Cellular proliferation and lipid metabolism: importance of lipoxygenases in modulating epidermal growth factor-dependent mitogenesis.

Authors:  T E Eling; W C Glasgow
Journal:  Cancer Metastasis Rev       Date:  1994-12       Impact factor: 9.264

  1 in total

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