[Migraine and acute myocardial infarction].

The relationship between migraine and cardiopathy has not been sufficiently established and controversy exists concerning its favoring role in coronary disease. Likewise, specific cephalea ("bregmatic") has been proposed as a manifestation of myocardial ischemia. With the aim of investigating this topic a protocol which collected the history and morphology of previous migraine, cephalea during the angina episode and cephalic response to vasodilators to 40 consecutive patients with acute myocardial infarction (AMI) admitted to the Coronary Unit of the Hospital 12 de Octubre in Madrid was applied. The results were compared with a control group. Migraine was more frequent in patients with AMI (25%) than in the control group (18.5%). Likewise, the beginning was later and the rhythm of the episodes greater. No specific cephalea was identified. The pain response to the nitrites did not depend on migraine history. The data suggests that determined forms of migraine may represent a risk factor of coronary disease. Epidemiologic studies are required to better know the natural history of the migraine.