Literature DB >> 8397778

Antigen-selected T-cell receptor diversity and self-nonself homology.

J L Casanova1, J L Maryanski.   

Abstract

Recent studies indicate that the T-cell receptor (TCR) repertoire selected by certain antigenic peptide-MHC combinations can be extremely diverse. This is in contrast to earlier studies reporting T-cell responses which were limited in terms of TCR diversity. In this viewpoint, we suggest these variations in TCR diversity may be explained by taking into account the homology between some antigens and self proteins to which T cells are tolerant.

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Year:  1993        PMID: 8397778     DOI: 10.1016/0167-5699(93)90140-G

Source DB:  PubMed          Journal:  Immunol Today        ISSN: 0167-5699


  26 in total

Review 1.  New methods for assessing T-cell responses.

Authors:  N Bercovici; M T Duffour; S Agrawal; M Salcedo; J P Abastado
Journal:  Clin Diagn Lab Immunol       Date:  2000-11

2.  Comparative T cell receptor repertoire selection by antigen after adoptive transfer: a glimpse at an antigen-specific preimmune repertoire.

Authors:  V Attuil; P Bucher; M Rossi; M Mutin; J L Maryanski
Journal:  Proc Natl Acad Sci U S A       Date:  2000-07-18       Impact factor: 11.205

Review 3.  Individuality of Ag-selected and preimmune TCR repertoires.

Authors:  J L Maryanski; V Attuil; A Hamrouni; M Mutin; M Rossi; A Aublin; P Bucher
Journal:  Immunol Res       Date:  2001       Impact factor: 2.829

4.  Multiple T-cell clones specific for the same foreign pMHC ligand can be generated from a single, ancestral TCR-VDJbeta precursor.

Authors:  Janet L Maryanski; Anne Aublin; Valérie Attuil-Audenis; Abdelbasset Hamrouni
Journal:  Immunol Res       Date:  2004       Impact factor: 2.829

5.  The immunopathology of regression in benign lichenoid keratosis, keratoacanthoma and halo nevus.

Authors:  Ilene B Bayer-Garner; Doina Ivan; Mary R Schwartz; Jaime A Tschen
Journal:  Clin Med Res       Date:  2004-05

6.  A similar pattern of interaction for different antibodies with a major antigenic site of foot-and-mouth disease virus: implications for intratypic antigenic variation.

Authors:  N Verdaguer; N Sevilla; M L Valero; D Stuart; E Brocchi; D Andreu; E Giralt; E Domingo; M G Mateu; I Fita
Journal:  J Virol       Date:  1998-01       Impact factor: 5.103

7.  Improved assessment of T-cell receptor (TCR) VB repertoire in clinical specimens: combination of TCR-CDR3 spectratyping with flow cytometry-based TCR VB frequency analysis.

Authors:  H Pilch; H Höhn; K Freitag; C Neukirch; A Necker; P Haddad; B Tanner; P G Knapstein; M J Maeurer
Journal:  Clin Diagn Lab Immunol       Date:  2002-03

8.  Susceptible MHC alleles, not background genes, select an autoimmune T cell reactivity.

Authors:  Thomas Stratmann; Natalia Martin-Orozco; Valérie Mallet-Designe; Laurent Poirot; Dorian McGavern; Grigoriy Losyev; Cathleen M Dobbs; Michael B A Oldstone; Kenji Yoshida; Hitoshi Kikutani; Diane Mathis; Christophe Benoist; Kathryn Haskins; Luc Teyton
Journal:  J Clin Invest       Date:  2003-09       Impact factor: 14.808

9.  [Latest aspects in psoriasis pathogenesis].

Authors:  J C Prinz
Journal:  Hautarzt       Date:  2003-02-12       Impact factor: 0.751

10.  Diversity of TCRAV and TCRBV sequences used by human T-cell clones specific for a minimal epitope of Bet v 1, the major birch pollen allergen.

Authors:  H Breiteneder; O Scheiner; R Hajek; W Hulla; R Hüttinger; G Fischer; D Kraft; C Ebner
Journal:  Immunogenetics       Date:  1995       Impact factor: 2.846

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