Literature DB >> 839722

Fibrosarcomas induced by cobalt chloride (CoCl2) in rats.

A A Shabaan, V Marks, M C Lancaster, G N Dufeu.   

Abstract

Hyperlipaemia persisted for more than 12 months in rats treated with cobalt chloride, 9 of 20 treated rats and 1 control rat died within the first year, and 8 of the surviving animals developed fibrosarcomas--in 4 of these the tumour was far removed from the injection sites. The results are discussed with reference to the use of cobalt chloride treatment for anaemia in patients with chronic renal failure.

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Year:  1977        PMID: 839722     DOI: 10.1258/002367777780959157

Source DB:  PubMed          Journal:  Lab Anim        ISSN: 0023-6772            Impact factor:   2.471


  3 in total

1.  Biological tolerance of different materials in bulk and nanoparticulate form in a rat model: sarcoma development by nanoparticles.

Authors:  Torsten Hansen; Gaëlle Clermont; Antonio Alves; Rosy Eloy; Christoph Brochhausen; Jean Pierre Boutrand; Antonietta M Gatti; C James Kirkpatrick
Journal:  J R Soc Interface       Date:  2006-12-22       Impact factor: 4.118

2.  Bioassay of metals for carcinogenesis: whole animals.

Authors:  A Furst
Journal:  Environ Health Perspect       Date:  1981-08       Impact factor: 9.031

Review 3.  Role of cobalt, iron, lead, manganese, mercury, platinum, selenium, and titanium in carcinogenesis.

Authors:  G Kazantzis
Journal:  Environ Health Perspect       Date:  1981-08       Impact factor: 9.031

  3 in total

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