Literature DB >> 8397152

Elevated secretory IgA antibodies to Epstein-Barr virus (EBV) and presence of EBV DNA and EBV receptors in patients with cervical carcinoma.

S Y Se Thoe1, K K Wong, R Pathmanathan, C K Sam, H M Cheng, U Prasad.   

Abstract

Epstein-Barr virus (EBV) receptors (EBV/C3d receptors) were detected, using the monoclonal antibody HB5, on 23 ectocervical and 5 endocervical biopsies of the uterine cervix. Elevated IgA titers against the viral capsid antigen and early antigen of EBV were also found in the cervical secretions from cervical carcinoma patients (83%), compared with samples from patients with cervical intraepithelial neoplasia (75%), herpes simplex virus-infected patients (0%), and gynecologic patients with nonmalignant conditions (0%). EBV DNA was present in 63% of cervical carcinoma biopsies detected by in situ hybridization. These observations suggest a positive association between EBV and carcinoma of the cervix.

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Year:  1993        PMID: 8397152     DOI: 10.1006/gyno.1993.1187

Source DB:  PubMed          Journal:  Gynecol Oncol        ISSN: 0090-8258            Impact factor:   5.482


  7 in total

1.  The mechanism of Epstein-Barr virus infection in nasopharyngeal carcinoma cells.

Authors:  C T Lin; C R Lin; G K Tan; W Chen; A N Dee; W Y Chan
Journal:  Am J Pathol       Date:  1997-05       Impact factor: 4.307

2.  Genitourinary manifestations of epstein-barr virus infections.

Authors:  Randi Leigh; Paul Nyirjesy
Journal:  Curr Infect Dis Rep       Date:  2009-11       Impact factor: 3.725

3.  Shedding of Epstein-Barr virus and cytomegalovirus from the genital tract of women in a periurban community in Andhra Pradesh, India.

Authors:  Michelle I Silver; Proma Paul; Pavani Sowjanya; Gayatri Ramakrishna; Haripriya Vedantham; Basany Kalpana; Keerti V Shah; Patti E Gravitt
Journal:  J Clin Microbiol       Date:  2011-04-27       Impact factor: 5.948

Review 4.  Genotypic mapping of HPV and assessment of EBV prevalence in endocervical lesions.

Authors:  J J O'Leary; R J Landers; M Crowley; I Healy; W F Kealy; J Hogan; C Cullinane; P Kelehan; C T Doyle
Journal:  J Clin Pathol       Date:  1997-11       Impact factor: 3.411

5.  Human papillomavirus and Epstein-Barr virus co-infection in cervical carcinoma in Algerian women.

Authors:  Abdelhalim Khenchouche; Nabila Sadouki; Arab Boudriche; Karim Houali; Abdelaziz Graba; Tadamasa Ooka; Abdelmadjid Bouguermouh
Journal:  Virol J       Date:  2013-11-19       Impact factor: 4.099

6.  Co-existing of HSV1/2 or EBV Infection with the Presence of High-Risk HPV DNA in Cervical Lesions in the Southwest of Iran.

Authors:  Negar Joharinia; Sajad Faghihinejad; Keyvan Seyedi; Ali Farhadi; Seyed Younes Hosseini; Akbar Safaei; Helen Bahrampour; Jamal Sarvari
Journal:  Asian Pac J Cancer Prev       Date:  2020-05-01

Review 7.  Co-infection of Epstein-Barr virus and human papillomavirus in human tumorigenesis.

Authors:  Ying Shi; Song-Ling Peng; Li-Fang Yang; Xue Chen; Yong-Guang Tao; Ya Cao
Journal:  Chin J Cancer       Date:  2016-01-22
  7 in total

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