Literature DB >> 8396681

Importance of the bovine papillomavirus P2443 promoter in the regulation of E2 and E5 expression.

B A Spalholz1.   

Abstract

The full-length bovine papillomavirus E2 gene product (E2TA), which has a direct role in DNA replication and functions as a transcriptional activator, can be expressed from an unspliced mRNA transcribed from the P2443 promoter or from spliced mRNAs transcribed from other upstream promoters. The regulation of E2 expression from these promoters is still in question. In the background of wild-type protein coding sequences, this study identified the P2443 promoter as the major source of E2TA as well as E5 expression in C127 cells.

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Year:  1993        PMID： 8396681      PMCID： PMC238053     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  42 in total

1.  A bovine papillomavirus constitutive enhancer is negatively regulated by the E2 repressor through competitive binding for a cellular factor.

Authors:  S B Vande Pol; P M Howley
Journal:  J Virol       Date:  1990-11       Impact factor: 5.103

2.  Transactivation of a bovine papilloma virus transcriptional regulatory element by the E2 gene product.

Authors:  B A Spalholz; Y C Yang; P M Howley
Journal:  Cell       Date:  1985-08       Impact factor: 41.582

3.  Transformation and replication in mouse cells of a bovine papillomavirus--pML2 plasmid vector that can be rescued in bacteria.

Authors:  N Sarver; J C Byrne; P M Howley
Journal:  Proc Natl Acad Sci U S A       Date:  1982-12       Impact factor: 11.205

4.  Messenger RNAs from the transforming region of bovine papilloma virus type I.

Authors:  A Stenlund; J Zabielski; H Ahola; J Moreno-Lopez; U Pettersson
Journal:  J Mol Biol       Date:  1985-04-20       Impact factor: 5.469

5.  Bovine papillomavirus contains multiple transforming genes.

Authors:  Y C Yang; H Okayama; P M Howley
Journal:  Proc Natl Acad Sci U S A       Date:  1985-02       Impact factor: 11.205

6.  The E2 transactivator of bovine papillomavirus type 1 is expressed from multiple promoters.

Authors:  P Vaillancourt; T Nottoli; J Choe; M R Botchan
Journal:  J Virol       Date:  1990-08       Impact factor: 5.103

7.  Characterization of the cis elements involved in basal and E2-transactivated expression of the bovine papillomavirus P2443 promoter.

Authors:  B A Spalholz; S B Vande Pol; P M Howley
Journal:  J Virol       Date:  1991-02       Impact factor: 5.103

8.  Localization and analysis of bovine papillomavirus type 1 transforming functions.

Authors:  N Sarver; M S Rabson; Y C Yang; J C Byrne; P M Howley
Journal:  J Virol       Date:  1984-11       Impact factor: 5.103

9.  Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

Authors:  C M Gorman; L F Moffat; B H Howard
Journal:  Mol Cell Biol       Date:  1982-09       Impact factor: 4.272

10.  Dissociation of transforming and trans-activation functions for bovine papillomavirus type 1.

Authors:  Y C Yang; B A Spalholz; M S Rabson; P M Howley
Journal:  Nature       Date:  1985 Dec 12-18       Impact factor: 49.962
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  3 in total

1.  A papillomavirus E2 phosphorylation mutant exhibits normal transient replication and transcription but is defective in transformation and plasmid retention.

Authors:  C W Lehman; D S King; M R Botchan
Journal:  J Virol       Date:  1997-05       Impact factor: 5.103

2.  Human papillomavirus type 31 replication modes during the early phases of the viral life cycle depend on transcriptional and posttranscriptional regulation of E1 and E2 expression.

Authors:  Walter G Hubert; Laimonis A Laimins
Journal:  J Virol       Date:  2002-03       Impact factor: 5.103

3.  Negative regulation of the bovine papillomavirus E5, E6, and E7 oncogenes by the viral E1 and E2 genes.

Authors:  S B Vande Pol; P M Howley
Journal:  J Virol       Date:  1995-01       Impact factor: 5.103
  3 in total

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