Literature DB >> 8394832

Defective association of dystrophin with sarcolemmal glycoproteins in the cardiomyopathic hamster heart.

Y Iwata1, H Nakamura, Y Mizuno, M Yoshida, E Ozawa, M Shigekawa.   

Abstract

In ventricular muscle from 30- to 60-day-old Bio 14.6 cardiomyopathic hamsters, dystrophin-associated glycoproteins of 43, 50 and 150 kDa are markedly reduced in abundance. In particular, the 50-kDa glycoprotein is totally deficient in the sarcolemma of myopathic ventricular myocytes as revealed by immunofluorescence microscopy. The dystrophin-glycoprotein complex formation is defective in the cardiomyopathic hamster heart, because dystrophin and the glycoproteins behave independently when digitonin-solubilized ventricular homogenates are fractionated on wheat germ agglutinin beads or anti-dystrophin immunoaffinity beads.

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Year:  1993        PMID: 8394832     DOI: 10.1016/0014-5793(93)80227-l

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  15 in total

1.  Extracellular matrix alterations in cardiomyopathy: The possible crucial role in the dilative form.

Authors:  V I Kapelko
Journal:  Exp Clin Cardiol       Date:  2001

2.  Cardiac syntrophin isoforms: species-dependent expression, association with dystrophin complex and subcellular localization.

Authors:  Yuko Iwata; Munekazu Shigekawa; Shigeo Wakabayashi
Journal:  Mol Cell Biochem       Date:  2005-01       Impact factor: 3.396

Review 3.  Mechanisms of resistance to pathogenesis in muscular dystrophies.

Authors:  J P Infante; V A Huszagh
Journal:  Mol Cell Biochem       Date:  1999-05       Impact factor: 3.396

Review 4.  Molecular Therapies for Muscular Dystrophies.

Authors:  Ava Y Lin; Leo H Wang
Journal:  Curr Treat Options Neurol       Date:  2018-06-21       Impact factor: 3.598

5.  Both hypertrophic and dilated cardiomyopathies are caused by mutation of the same gene, delta-sarcoglycan, in hamster: an animal model of disrupted dystrophin-associated glycoprotein complex.

Authors:  A Sakamoto; K Ono; M Abe; G Jasmin; T Eki; Y Murakami; T Masaki; T Toyo-oka; F Hanaoka
Journal:  Proc Natl Acad Sci U S A       Date:  1997-12-09       Impact factor: 11.205

6.  Enhanced Na+/H+ exchange activity contributes to the pathogenesis of muscular dystrophy via involvement of P2 receptors.

Authors:  Yuko Iwata; Yuki Katanosaka; Takashi Hisamitsu; Shigeo Wakabayashi
Journal:  Am J Pathol       Date:  2007-09-06       Impact factor: 4.307

7.  Sarcoglycan complex is selectively lost in dystrophic hamster muscle.

Authors:  Y Mizuno; S Noguchi; H Yamamoto; M Yoshida; I Nonaka; S Hirai; E Ozawa
Journal:  Am J Pathol       Date:  1995-02       Impact factor: 4.307

Review 8.  Our trails and trials in the subsarcolemmal cytoskeleton network and muscular dystrophy researches in the dystrophin era.

Authors:  Eijiro Ozawa
Journal:  Proc Jpn Acad Ser B Phys Biol Sci       Date:  2010       Impact factor: 3.493

9.  A common disease-associated missense mutation in alpha-sarcoglycan fails to cause muscular dystrophy in mice.

Authors:  Kazuhiro Kobuke; Federica Piccolo; Keith W Garringer; Steven A Moore; Eileen Sweezer; Baoli Yang; Kevin P Campbell
Journal:  Hum Mol Genet       Date:  2008-02-05       Impact factor: 6.150

10.  Sarcospan: a small protein with large potential for Duchenne muscular dystrophy.

Authors:  Jamie L Marshall; Rachelle H Crosbie-Watson
Journal:  Skelet Muscle       Date:  2013-01-03       Impact factor: 4.912

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