| Literature DB >> 8394815 |
I M Hoepelman1, W H Havinga, R A Benne, M Zwinkels, M A de Wit, H A de Hond, T A Boon, M R Visser, F W van Asbeck, J Verhoef.
Abstract
Seventy patients with complicated urinary tract infections were treated with either lomefloxacin (400 mg once daily) or norfloxacin (400 mg twice daily) for 10 to 14 days. A total of 19 (86%) of 22 patients treated with lomefloxacin and 20 (74%) of 27 patients treated with norfloxacin were cured, as defined by a negative culture five to nine days after completion of therapy (p = 0.09). After four to six weeks, the figures were 56% for lomefloxacin and 48% for norfloxacin. Adverse effects in the lomefloxacin group were observed on 20 occasions in 12 patients (one stopped treatment) compared to nine occasions in five patients treated with norfloxacin (difference not significant).Entities:
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Year: 1993 PMID： 8394815 DOI： 10.1007/bf01964430
Source DB: PubMed Journal: Eur J Clin Microbiol Infect Dis ISSN： 0934-9723 Impact factor: 3.267