Literature DB >> 8394103

A novel model of a metastatic human breast tumour xenograft line.

J Hurst1, N Maniar, J Tombarkiewicz, F Lucas, C Roberson, Z Steplewski, W James, J Perras.   

Abstract

The GI-101 human breast tumour xenograft line is unique in that it spontaneously metastasizes to the lungs of athymic murine hosts from subcutaneous trochar implants. Both tumour and lung metastases are positive for normal human breast tissue markers. GI-101 also is positive for the p53 antigen but negative for the c-erbB-2 oncogene.

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Year:  1993        PMID: 8394103      PMCID: PMC1968562          DOI: 10.1038/bjc.1993.327

Source DB:  PubMed          Journal:  Br J Cancer        ISSN: 0007-0920            Impact factor:   7.640


  3 in total

Review 1.  p53 expression in human breast cancer.

Authors:  A L Harris
Journal:  Adv Cancer Res       Date:  1992       Impact factor: 6.242

2.  In vitro enhancement of cis-platinum antitumor activity by caffeine and pentoxifylline in a human ovarian cell line.

Authors:  M A Schiano; B U Sevin; J Perras; R Ramos; E H Wolloch; H E Averette
Journal:  Gynecol Oncol       Date:  1991-10       Impact factor: 5.482

3.  Heterotransplantation of human breast carcinomas in nude mice. Correlation between successful heterotransplants, poor prognosis and amplification of the HER-2/neu oncogene.

Authors:  B C Giovanella; D M Vardeman; L J Williams; D J Taylor; P D de Ipolyi; P J Greeff; J S Stehlin; A Ullrich; R Cailleau; D J Slamon
Journal:  Int J Cancer       Date:  1991-01-02       Impact factor: 7.396

  3 in total
  12 in total

1.  Angiogenesis Inhibitor O-(Chloroacetyl-carbamoyl) fumagillol (TNP-470) Inhibits Tumor Angiogenesis, Growth and Spontaneous Metastasis of MKL-4 Human Breast Cancer Cells in Female Athymic Nude Mice.

Authors: 
Journal:  Breast Cancer       Date:  1994-12-30       Impact factor: 4.239

2.  Expression of molecular biomarkers in primary breast tumors implanted into a surrogate host: increased levels of cyclins correlate with tumor progression.

Authors:  G Wani; I Noyes; G E Milo; S M D'Ambrosio
Journal:  Mol Med       Date:  1997-04       Impact factor: 6.354

3.  Selection of more aggressive variants of the gI101A human breast cancer cell line: a model for analyzing the metastatic phenotype of breast cancer.

Authors:  Dina Chelouche Lev; Galina Kiriakova; Janet E Price
Journal:  Clin Exp Metastasis       Date:  2003       Impact factor: 5.150

4.  Genomic signatures of breast cancer metastasis.

Authors:  V Urquidi; S Goodison
Journal:  Cytogenet Genome Res       Date:  2007       Impact factor: 1.636

5.  Oncolytic vaccinia virus GLV-1h68 strain shows enhanced replication in human breast cancer stem-like cells in comparison to breast cancer cells.

Authors:  Huiqiang Wang; Nanhai G Chen; Boris R Minev; Aladar A Szalay
Journal:  J Transl Med       Date:  2012-08-17       Impact factor: 5.531

6.  Enhanced tumor therapy using vaccinia virus strain GLV-1h68 in combination with a β-galactosidase-activatable prodrug seco-analog of duocarmycin SA.

Authors:  C M Seubert; J Stritzker; M Hess; U Donat; J B Sturm; N Chen; J M von Hof; B Krewer; L F Tietze; I Gentschev; A A Szalay
Journal:  Cancer Gene Ther       Date:  2010-09-10       Impact factor: 5.987

7.  Mouse models of breast cancer metastasis.

Authors:  Anna Fantozzi; Gerhard Christofori
Journal:  Breast Cancer Res       Date:  2006       Impact factor: 6.466

8.  Development of a new metastatic human breast carcinoma xenograft line.

Authors:  R R Mehta; J M Graves; A Shilkaitis; T K Das Gupta
Journal:  Br J Cancer       Date:  1998-02       Impact factor: 7.640

9.  Imaging of intratumoral inflammation during oncolytic virotherapy of tumors by 19F-magnetic resonance imaging (MRI).

Authors:  Stephanie Weibel; Thomas Christian Basse-Luesebrink; Michael Hess; Elisabeth Hofmann; Carolin Seubert; Johanna Langbein-Laugwitz; Ivaylo Gentschev; Volker Jörg Friedrich Sturm; Yuxiang Ye; Thomas Kampf; Peter Michael Jakob; Aladar A Szalay
Journal:  PLoS One       Date:  2013-02-18       Impact factor: 3.240

10.  Overexpression of mutant p53 and c-erbB-2 proteins and breast tumour take in mice.

Authors:  R R Mehta; J M Graves; M A Warso; T K Das Gupta
Journal:  Br J Cancer       Date:  1995-11       Impact factor: 7.640

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