Literature DB >> 8393850

Lagunamycin, a novel 5-lipoxygenase inhibitor. I. Taxonomy, fermentation, physico-chemical properties and biological characteristics.

Y Nihei1, M Hasegawa, K Suzuki, S Yamamoto, M Hanada, T Furumai, Y Fukagawa, T Oki.   

Abstract

Lagunamycin, a novel 5-lipoxygenase inhibitor, was isolated from the culture broth of Streptomyces sp. AA0310. This compound showed potent rat 5-lipoxygenase inhibitory activity (IC50 6.08 microM) without lipid peroxidation.

Entities:  

Mesh:

Substances:

Year:  1993        PMID: 8393850     DOI: 10.7164/antibiotics.46.900

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  1 in total

1.  A nitrous acid biosynthetic pathway for diazo group formation in bacteria.

Authors:  Yoshinori Sugai; Yohei Katsuyama; Yasuo Ohnishi
Journal:  Nat Chem Biol       Date:  2015-12-21       Impact factor: 15.040

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.