Literature DB >> 8392436

Integration of Epstein Barr virus near the breakpoint of a translocation 11;19 in a Burkitt's lymphoma cell line.

J Wolf1, M Pawlita, A Jox, S Kohls, S Bartnitzke, V Diehl, J Bullerdiek.   

Abstract

The physical state of Epstein Barr virus (EBV) DNA was analyzed in the Burkitt's lymphoma (BL) cell line BL60 and in the autologous EBV-immortalized lymphoblastoid cell line (LCL) IARC 277 by Gardella gel analysis, Southern blotting, and nonradioactive in situ hybridization to metaphase chromosomes. Although only episomal viral DNA was detected in the LCL, the 6-12 copies of EBV DNA in the BL cell line are integrated in one site of the host cell genome. The integration site is located near the breakpoint of a translocation 11;19 which is present in this cell line in addition to the BL-specific t(8;22).

Entities:  

Mesh：

Substances：

Year:  1993        PMID： 8392436     DOI： 10.1016/0165-4608(93)90158-i

Source DB:  PubMed          Journal:  Cancer Genet Cytogenet        ISSN： 0165-4608


  4 in total

Review 1.  The search for a gene involved in the determination of limited duplicative capacity in human cells.

Authors:  E Calef; A Scotto d'Abusco; E Bianchi; S Gargano; A Fruscalzo
Journal:  Genetica       Date:  1994       Impact factor: 1.082

2.  Integration of Epstein-Barr virus into chromosome 6q15 of Burkitt lymphoma cell line (Raji) induces loss of BACH2 expression.

Authors:  Tetsuya Takakuwa; Wen-Juan Luo; Maria Francisca Ham; Femiko Sakane-Ishikawa; Naoki Wada; Katsuyuki Aozasa
Journal:  Am J Pathol       Date:  2004-03       Impact factor: 4.307

Review 3.  Viral carcinogenesis: factors inducing DNA damage and virus integration.

Authors:  Yan Chen; Vonetta Williams; Maria Filippova; Valery Filippov; Penelope Duerksen-Hughes
Journal:  Cancers (Basel)       Date:  2014-10-22       Impact factor: 6.639

4.  Non-Random Pattern of Integration for Epstein-Barr Virus with Preference for Gene-Poor Genomic Chromosomal Regions into the Genome of Burkitt Lymphoma Cell Lines.

Authors:  Snjezana Janjetovic; Juliane Hinke; Saranya Balachandran; Nuray Akyüz; Petra Behrmann; Carsten Bokemeyer; Judith Dierlamm; Eva Maria Murga Penas
Journal:  Viruses       Date:  2022-01-04       Impact factor: 5.048
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.