Literature DB >> 8392153

Immunocytochemical localization of rat substance P receptor in the striatum.

R Shigemoto1, Y Nakaya, S Nomura, R Ogawa-Meguro, H Ohishi, T Kaneko, S Nakanishi, N Mizuno.   

Abstract

A trp E fusion protein containing a C-terminal portion of the rat substance P receptor (SPR) was expressed in bacteria and used to produce an antibody. The antibody specifically reacted with SPR expressed in a mammalian cell line and rat striatum. Light and electron microscope analyses of the rat striatum revealed intense SPR-like immunoreactivity in neuronal somata and dendrites. These immunoreactive neurons constituted approximately 3% of the total population of striatal neurons; they were putative interneurons of large and medium-sized aspiny type.

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Year:  1993        PMID： 8392153     DOI： 10.1016/0304-3940(93)90311-8

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN： 0304-3940            Impact factor:   3.046


  15 in total

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7.  Actions of substance P on rat neostriatal neurons in vitro.

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8.  Synaptic relationship between substance P and the substance P receptor: light and electron microscopic characterization of the mismatch between neuropeptides and their receptors.

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