Literature DB >> 8391692

Enkephalin antisense peptides: design, synthesis, and biological activity.

P K Misra1, W Haq, S B Katti, K B Mathur, R Raghubir, G K Patnaik, B N Dhawan.   

Abstract

The antisense mRNA complementary to the sense strand of Metenkephalin encodes the antisense peptides, His-Glu-Ala-Pro-Ile (compound 88/62). The antisense peptide and its (Gln1)-analogue (compound 88/63) have synergestic effects on the opioid activity of Met-enkephalin in the GPI test system.

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Year:  1993        PMID: 8391692     DOI: 10.1023/a:1018991212271

Source DB:  PubMed          Journal:  Pharm Res        ISSN: 0724-8741            Impact factor:   4.200


  11 in total

1.  Synthetic analgesics. II. Dithienylbutenyl- and dithienylbutylamines.

Authors:  N B EDDY; D LEIMBACH
Journal:  J Pharmacol Exp Ther       Date:  1953-03       Impact factor: 4.030

2.  Conformational behavior of fragments of adrenocorticotropin and their antisense peptides determined by NMR spectroscopy and CD spectropolarimetry.

Authors:  E S Najem; A Corigliano-Murphy; J A Ferretti
Journal:  FEBS Lett       Date:  1989-07-03       Impact factor: 4.124

3.  Anti-sense peptide recognition of sense peptides: direct quantitative characterization with the ribonuclease S-peptide system using analytical high-performance affinity chromatography.

Authors:  Y Shai; M Flashner; I M Chaiken
Journal:  Biochemistry       Date:  1987-02-10       Impact factor: 3.162

4.  Isolation and structural organization of the human preproenkephalin gene.

Authors:  M Noda; Y Teranishi; H Takahashi; M Toyosato; M Notake; S Nakanishi; S Numa
Journal:  Nature       Date:  1982-06-03       Impact factor: 49.962

5.  Hydropathic anti-complementarity of amino acids based on the genetic code.

Authors:  J E Blalock; E M Smith
Journal:  Biochem Biophys Res Commun       Date:  1984-05-31       Impact factor: 3.575

6.  A simple method for displaying the hydropathic character of a protein.

Authors:  J Kyte; R F Doolittle
Journal:  J Mol Biol       Date:  1982-05-05       Impact factor: 5.469

7.  Angiotensin 'antipeptides': (-)messenger RNA complementary to human angiotensin II (+)messenger RNA encodes an angiotensin receptor antagonist.

Authors:  G J Moore; R C Ganter; K J Franklin
Journal:  Biochem Biophys Res Commun       Date:  1989-05-15       Impact factor: 3.575

8.  Similarity between the corticotropin (ACTH) receptor and a peptide encoded by an RNA that is complementary to ACTH mRNA.

Authors:  K L Bost; E M Smith; J E Blalock
Journal:  Proc Natl Acad Sci U S A       Date:  1985-03       Impact factor: 11.205

9.  Kinetic parameters of narcotic agonists and antagonists, with particular reference to N-allylnoroxymorphone (naloxone).

Authors:  H W Kosterlitz; A J Watt
Journal:  Br J Pharmacol Chemother       Date:  1968-06

10.  A novel arginine vasopressin-binding peptide that blocks arginine vasopressin modulation of immune function.

Authors:  H M Johnson; B A Torres
Journal:  J Immunol       Date:  1988-10-01       Impact factor: 5.422

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