Literature DB >> 8391572

Enhanced urinary excretion of leukotriene E4 in patients with mevalonate kinase deficiency.

E Mayatepek1, G F Hoffmann, H J Bremer.   

Abstract

In patients with mevalonate kinase deficiency, urinary excretion of the leukotriene LTE4 was found to be elevated. A positive linear relationship between increased urinary excretion of mevalonate and LTE4 (n = 5) suggests that increased cysteinyl leukotriene synthesis is involved in the pathomechanisms of this disease.

Entities:  

Mesh：

Substances：

Year:  1993        PMID： 8391572     DOI： 10.1016/s0022-3476(05)81548-3

Source DB:  PubMed          Journal:  J Pediatr        ISSN： 0022-3476            Impact factor:   4.406


  5 in total

Review 1.  The measurement of leukotrienes in human fluids.

Authors:  J Y Westcott
Journal:  Clin Rev Allergy Immunol       Date:  1999 Spring-Summer       Impact factor: 8.667

2.  Increased urinary leukotriene E(4) during febrile attacks in the hyperimmunoglobulinaemia D and periodic fever syndrome.

Authors:  J Frenkel; M A Willemsen; C M Weemaes; L Dorland; E Mayatepek
Journal:  Arch Dis Child       Date:  2001-08       Impact factor: 3.791

3.  SSIEM Award. Impaired metabolism of leukotrienes in inherited metabolic disorders.

Authors:  E Mayatepek; G F Hoffmann
Journal:  J Inherit Metab Dis       Date:  1994       Impact factor: 4.982

4.  Effect of plasma alpha-tocopherol on leukotriene E4 excretion in genetic vitamin E deficiency.

Authors:  A Kohlschütter; E Mayatepek; B Finckh; C Hübner
Journal:  J Inherit Metab Dis       Date:  1997-08       Impact factor: 4.982

Review 5.  Mevalonate kinase deficiencies: from mevalonic aciduria to hyperimmunoglobulinemia D syndrome.

Authors:  Dorothea Haas; Georg F Hoffmann
Journal:  Orphanet J Rare Dis       Date:  2006-04-26       Impact factor: 4.123
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.