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Literature DB >> 8391494

On the potential role of proopiomelanocortin in skin physiology and pathology.

Abstract

Pro-opiomelanocortin (POMC) is the precursor of ACTH, alpha-MSH and beta-endorphin, neuropeptides with multiple regulatory functions. Both the pituitary gland and peripheral tissues such as mammalian skin are capable of generating POMC-derived neuropeptides. Mammalian skin is also a target for POMC products; their possible roles in skin physiology and pathology are discussed in this communication.

Entities: Gene Species

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Year: 1993 PMID： 8391494 DOI： 10.1016/0303-7207(93)90131-3

Source DB: PubMed Journal: Mol Cell Endocrinol ISSN： 0303-7207 Impact factor: 4.102

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Cited

27 in total

1. Melanocortin-1 receptor polymorphisms and risk of melanoma: is the association explained solely by pigmentation phenotype?

Authors: J S Palmer; D L Duffy; N F Box; J F Aitken; L E O'Gorman; A C Green; N K Hayward; N G Martin; R A Sturm
Journal: Am J Hum Genet Date: 2000-01 Impact factor: 11.025

2. Human keratinocytes express functional alpha-MSH (MC1-R) receptors.

Authors: J L Curry; W Pinto; B J Nickoloff; A T Slominski
Journal: In Vitro Cell Dev Biol Anim Date: 2001-04 Impact factor: 2.416

3. Collapse and restoration of MHC class-I-dependent immune privilege: exploiting the human hair follicle as a model.

Authors: Taisuke Ito; Natsuho Ito; Albrecht Bettermann; Yoshiki Tokura; Masahiro Takigawa; Ralf Paus
Journal: Am J Pathol Date: 2004-02 Impact factor: 4.307

Review 4. Neuroendocrine system of the skin.

Authors: Andrzej Slominski
Journal: Dermatology Date: 2005 Impact factor: 5.366

On the potential role of proopiomelanocortin in skin physiology and pathology.

1. Melanocortin-1 receptor polymorphisms and risk of melanoma: is the association explained solely by pigmentation phenotype?

2. Human keratinocytes express functional alpha-MSH (MC1-R) receptors.

3. Collapse and restoration of MHC class-I-dependent immune privilege: exploiting the human hair follicle as a model.

Review 4. Neuroendocrine system of the skin.

Review 5. Corticotropin releasing hormone and the skin.

6. Neuroendocrinology of the skin: An overview and selective analysis.

7. Pleiotropic effects of corticotropin releasing hormone on normal human skin keratinocytes.

8. Corticotropin releasing hormone and related peptides can act as bioregulatory factors in human keratinocytes.

Review 9. Signaling pathways in melanosome biogenesis and pathology.

Review 10. Differential expression of HPA axis homolog in the skin.