Literature DB >> 8390414

DNA-dependent RNA polymerase enzymes affected in uraemic lymphocyte cells.

R Adamiec1, Z Szewczyk, J Szopa.   

Abstract

The DNA-dependent RNA polymerase activity and endonucleases in uraemic lymphocyte cells were investigated. It was found that the activity and quantity in three classes of polymerases are remarkably reduced. The reduction in enzyme activity is accompanied by increasing endonuclease activity. The relationship of polymerase enzymes with endonucleases is discussed.

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Year:  1993        PMID: 8390414     DOI: 10.1007/bf02552261

Source DB:  PubMed          Journal:  Int Urol Nephrol        ISSN: 0301-1623            Impact factor:   2.370


  6 in total

1.  Cleavage of the 190-kDa subunit of DNA-dependent RNA polymerase I yields small polypeptides capable of degrading DNA.

Authors:  J Szopa; K M Rose
Journal:  J Biol Chem       Date:  1986-07-05       Impact factor: 5.157

2.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

Review 3.  Transcription of cloned eukaryotic ribosomal RNA genes.

Authors:  B Sollner-Webb; J Tower
Journal:  Annu Rev Biochem       Date:  1986       Impact factor: 23.643

4.  DNA-dependent RNA polymerase II from nuclei of suspension-cultured tobacco cells.

Authors:  J Szopa; K G Wagner
Journal:  Planta       Date:  1984-09       Impact factor: 4.116

5.  Lipopolysaccharide-mediated induction of RNA polymerase I activity and amount in murine B lymphocytes.

Authors:  S L Liu; K M Rose
Journal:  J Biol Chem       Date:  1986-06-25       Impact factor: 5.157

6.  Is an increase of deoxyribonucleases activity in uraemic lymphocytes caused by their augmented synthesis in these cells?

Authors:  R Adamiec; Z Szewczyk; R Szmidziński; J Szopa
Journal:  Clin Chim Acta       Date:  1993-11-30       Impact factor: 3.786

  6 in total

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