Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Synthesis and reactions of the highly mutagenic 7,8-diol 9,10-epoxides of the carcinogen benzo[a]pyrene.

× No keyword cloud information.

16 in total

1. Highly diastereoselective synthesis of nucleoside adducts from the carcinogenic benzo[a]pyrene diol epoxide and a computational analysis.

Authors: Mahesh K Lakshman; John C Keeler; Felix N Ngassa; John H Hilmer; Padmanava Pradhan; Barbara Zajc; Kathryn A Thomasson
Journal: J Am Chem Soc Date: 2007-01-10 Impact factor: 15.419

2. Tumorigenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides in newborn mice: exceptional activity of (+)-7beta,8alpha-dihydroxy-9alpha,10alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene.

Authors: M K Buening; P G Wislocki; W Levin; H Yagi; D R Thakker; H Akagi; M Koreeda; D M Jerina; A H Conney
Journal: Proc Natl Acad Sci U S A Date: 1978-11 Impact factor: 11.205

3. Metabolic activations of polycyclic hydrocarbons. Structure-activity relationships.

Authors: R E Lehr; D M Jerina
Journal: Arch Toxicol Date: 1977-12-30 Impact factor: 5.153

4. Three prime exonuclease I (TREX1) is Fos/AP-1 regulated by genotoxic stress and protects against ultraviolet light and benzo(a)pyrene-induced DNA damage.

Authors: Markus Christmann; Maja T Tomicic; Dorthe Aasland; Nicole Berdelle; Bernd Kaina
Journal: Nucleic Acids Res Date: 2010-05-28 Impact factor: 16.971

5. Role of diaxial versus diequatorial hydroxyl groups in the tumorigenic activity of a benzo[a]pyrene bay-region diol epoxide.

Authors: R L Chang; A W Wood; A H Conney; H Yagi; J M Sayer; D R Thakker; D M Jerina; W Levin
Journal: Proc Natl Acad Sci U S A Date: 1987-12 Impact factor: 11.205

6. Epoxidation of (+/-)-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene during (bi)sulfite autoxidation: activation of a procarcinogen by a cocarcinogen.

Authors: G A Reed; J F Curtis; C Mottley; T E Eling; R P Mason
Journal: Proc Natl Acad Sci U S A Date: 1986-10 Impact factor: 11.205

7. Crystal and molecular structure of a benzo[a]pyrene 7,8-diol 9,10-epoxide N2-deoxyguanosine adduct: absolute configuration and conformation.

Authors: Isabella L Karle; Haruhiko Yagi; Jane M Sayer; Donald M Jerina
Journal: Proc Natl Acad Sci U S A Date: 2004-02-02 Impact factor: 11.205

Synthesis and reactions of the highly mutagenic 7,8-diol 9,10-epoxides of the carcinogen benzo[a]pyrene.