Literature DB >> 8389684

Human connexin43 gene locus, GJA1, sublocalized to band 6q21-->q23.2.

I A Corcos1, E U Meese, R Loch-Caruso.   

Abstract

Gap junctions permit transfer of small molecules directly between cells. Several laboratories have mapped the human gap junction protein subunit, connexin43 (locus designation, GJA1), to overlapping regions of chromosome 6, localizing GJA1 to 6q14-->q24. We have sublocalized human GJA1 to a very small region. 6q21-->q23.2, using a human x rodent somatic cell hybrid mapping panel and a rat connexin43 cDNA probe.

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Year:  1993        PMID: 8389684     DOI: 10.1159/000133554

Source DB:  PubMed          Journal:  Cytogenet Cell Genet        ISSN: 0301-0171


  2 in total

1.  Physical mapping of connexin 32 (GJB1) and 43 (GJA1) genes to bovine chromosomes Xq22 and 9q15/16 by fluorescence in situ hybridization.

Authors:  B Castiglioni; L Ferretti; M L Tenchini; A Mezzelani; T Simonic; S Duga
Journal:  Mamm Genome       Date:  1996-08       Impact factor: 2.957

2.  Novel mutations in the connexin43 (GJA1) and GJA1 pseudogene may contribute to nonsyndromic hearing loss.

Authors:  Hui-Mei Hong; Jiann-Jou Yang; Jia-Ching Shieh; Mei-Ling Lin; Mei-Ling Li; Shuan-Yow Li
Journal:  Hum Genet       Date:  2010-02-04       Impact factor: 4.132

  2 in total

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