Literature DB >> 8386941

EPR spin-trapping study of nitric oxide formation during bilateral carotid occlusion in the rat.

S Sato1, T Tominaga, T Ohnishi, S T Ohnishi.   

Abstract

The formation of nitric oxide (NO) radicals was demonstrated by electron paramagnetic resonance spectroscopy in the rat during varying degrees of brain ischemia. Diethyldithiocarbamate and Fe-citrate were used as in vivo spin-trapping reagents. The signal of NO spin adducts increased in accordance with the degree of ischemic insults. The formation of NO radicals was inhibited by NG-nitro-L-arginine methyl ester.

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Year:  1993        PMID: 8386941     DOI: 10.1016/0925-4439(93)90111-d

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  5 in total

1.  Abnormal cerebral haemodynamics in perinatally asphyxiated neonates related to outcome.

Authors:  J H Meek; C E Elwell; D C McCormick; A D Edwards; J P Townsend; A L Stewart; J S Wyatt
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  1999-09       Impact factor: 5.747

2.  Augmentation of nitric oxide, superoxide, and peroxynitrite production during cerebral ischemia and reperfusion in the rat.

Authors:  L J Forman; P Liu; R G Nagele; K Yin; P Y Wong
Journal:  Neurochem Res       Date:  1998-02       Impact factor: 3.996

Review 3.  Targeting reactive nitrogen species: a promising therapeutic strategy for cerebral ischemia-reperfusion injury.

Authors:  Xing-miao Chen; Han-sen Chen; Ming-jing Xu; Jian-gang Shen
Journal:  Acta Pharmacol Sin       Date:  2012-07-30       Impact factor: 6.150

4.  Polydeoxyribonucleotides and nitric oxide release from guinea-pig hearts during ischaemia and reperfusion.

Authors:  E Masini; M Lupini; L Mugnai; S Raspanti; P F Mannaioni
Journal:  Br J Pharmacol       Date:  1995-06       Impact factor: 8.739

Review 5.  Nitric oxide and the brain. Part 2: Effects following neonatal brain injury-friend or foe?

Authors:  Dimitrios Angelis; Rashmin Savani; Lina Chalak
Journal:  Pediatr Res       Date:  2020-06-20       Impact factor: 3.756

  5 in total

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