Literature DB >> 8386674

Calcium ionophore plus excision induce a large conductance chloride channel in membrane patches of human colon carcinoma cells HT-29cl.19A.

R B Bajnath1, J A Groot, H R de Jonge, M Kansen, J Bijman.   

Abstract

In excised inside-out membrane patches of the human colon carcinoma HT-29cl.19A cells a large conductance (373 +/- 10 pS) chloride channel was found. Channel activity could only be observed after excision of patches from cells incubated with calcium ionophore. The channel was never observed in cell-attached patches. The channel was strongly voltage dependent, being open only between +30 and -30 mV clamp potentials. The selectivity sequence among anions, deduced from reversal potentials, was I > Br > Cl > F > gluconate. The PNa/PCl was 0.09. Although a similar type of channel has been described earlier, this is the first report stating its appearance in patches of intestinal epithelial cells requiring the combined action of Ca2+ ionophore and excision, suggesting its control by an intracellular compound.

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Year:  1993        PMID： 8386674     DOI： 10.1007/bf01923409

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  16 in total

1.  A large, multiple-conductance chloride channel in normal human T lymphocytes.

Authors:  L C Schlichter; R Grygorczyk; P A Pahapill; C Grygorczyk
Journal:  Pflugers Arch       Date:  1990-06       Impact factor: 3.657

2.  A large anion-selective channel has seven conductance levels.

Authors:  M E Krouse; G T Schneider; P W Gage
Journal:  Nature       Date:  1986 Jan 2-8       Impact factor: 49.962

3.  Single-channel recordings of apical membrane chloride conductance in A6 epithelial cells.

Authors:  D J Nelson; J M Tang; L G Palmer
Journal:  J Membr Biol       Date:  1984       Impact factor: 1.843

4.  Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches.

Authors:  O P Hamill; A Marty; E Neher; B Sakmann; F J Sigworth
Journal:  Pflugers Arch       Date:  1981-08       Impact factor: 3.657

5.  Single voltage-dependent chloride-selective channels of large conductance in cultured rat muscle.

Authors:  A L Blatz; K L Magleby
Journal:  Biophys J       Date:  1983-08       Impact factor: 4.033

6.  Expression of the cystic fibrosis gene in non-epithelial invertebrate cells produces a regulated anion conductance.

Authors:  N Kartner; J W Hanrahan; T J Jensen; A L Naismith; S Z Sun; C A Ackerley; E F Reyes; L C Tsui; J M Rommens; C E Bear
Journal:  Cell       Date:  1991-02-22       Impact factor: 41.582

7.  Electrophysiological studies of forskolin-induced changes in ion transport in the human colon carcinoma cell line HT-29 cl.19A: lack of evidence for a cAMP-activated basolateral K+ conductance.

Authors:  R B Bajnath; C Augeron; C L Laboisse; J Bijman; H R de Jonge; J A Groot
Journal:  J Membr Biol       Date:  1991-06       Impact factor: 1.843

8.  Anion channels in a human pancreatic cancer cell line (Capan-1) of ductal origin.

Authors:  F Becq; M Fanjul; I Mahieu; Z Berger; M Gola; E Hollande
Journal:  Pflugers Arch       Date:  1992-01       Impact factor: 3.657

9.  Biphasic increase of apical Cl- conductance by muscarinic stimulation of HT-29cl.19A human colon carcinoma cell line: evidence for activation of different Cl- conductances by carbachol and forskolin.

Authors:  R B Bajnath; K Dekker; A B Vaandrager; H R de Jonge; J A Groot
Journal:  J Membr Biol       Date:  1992-04       Impact factor: 1.843

10.  Regulation of apical Cl- conductance and basolateral K+ conductances by phorbol esters in HT-29cl.19A cells.

Authors:  R B Bajnath; M H van Hoeve; H R de Jonge; J A Groot
Journal:  Am J Physiol       Date:  1992-10
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  7 in total

Review 1.  The properties, functions, and pathophysiology of maxi-anion channels.

Authors:  Ravshan Z Sabirov; Petr G Merzlyak; Md Rafiqul Islam; Toshiaki Okada; Yasunobu Okada
Journal:  Pflugers Arch       Date:  2016-01-06       Impact factor: 3.657

2.  Proteins of cytosol and amniotic fluid increase the voltage dependence of human type-1 porin.

Authors:  M Heiden; K Kroll; F P Thinnes; N Hilschmann
Journal:  J Bioenerg Biomembr       Date:  1996-04       Impact factor: 2.945

Review 3.  The maxi-anion channel: a classical channel playing novel roles through an unidentified molecular entity.

Authors:  Ravshan Z Sabirov; Yasunobu Okada
Journal:  J Physiol Sci       Date:  2008-12-09       Impact factor: 2.781

4.  Epithelia of the ovine and bovine forestomach express basolateral maxi-anion channels permeable to the anions of short-chain fatty acids.

Authors:  Maria I Georgi; Julia Rosendahl; Franziska Ernst; Dorothee Günzel; Jörg R Aschenbach; Holger Martens; Friederike Stumpff
Journal:  Pflugers Arch       Date:  2013-11-17       Impact factor: 3.657

5.  ATP release via anion channels.

Authors:  Ravshan Z Sabirov; Yasunobu Okada
Journal:  Purinergic Signal       Date:  2005-12-03       Impact factor: 3.765

Review 6.  Extramitochondrial porin: facts and hypotheses.

Authors:  G Báthori; I Parolini; I Szabó; F Tombola; A Messina; M Oliva; M Sargiacomo; V De Pinto; M Zoratti
Journal:  J Bioenerg Biomembr       Date:  2000-02       Impact factor: 2.945

Review 7.  The ATP-Releasing Maxi-Cl Channel: Its Identity, Molecular Partners and Physiological/Pathophysiological Implications.

Authors:  Ravshan Z Sabirov; Md Rafiqul Islam; Toshiaki Okada; Petr G Merzlyak; Ranokhon S Kurbannazarova; Nargiza A Tsiferova; Yasunobu Okada
Journal:  Life (Basel)       Date:  2021-05-31
  7 in total

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