Literature DB >> 8385185

The Relaxometer: a complete and comprehensive computer-controlled neuromuscular transmission measurement system developed for clinical research on muscle relaxants.

C J Rowaan1, R H Vandenbrom, J M Wierda.   

Abstract

The Relaxometer is a computer-controlled system developed for reliable clinical experimental measurements on neuromuscular block. This system is based on an adapted personal computer (Atari 1040 ST) with a monochrome monitor (Atari SM 124), and a microcomputer-driven slave unit (stimulator). There are several stimulation patterns available: single twitch at 0.1 and 1 Hz, single train-of-four, continuous train-of-four every 12 seconds, and tetanic stimulation at 50 Hz for 5 seconds followed by posttetanic count. The system is equipped with a temperature module for continuous monitoring of the skin/muscle temperature and a rechargeable battery to allow uninterrupted measurements if the apparatus is disconnected from the line power. All acquired data, computer-calculated parameters (onset time, duration time, recovery index, train-of-four ratio, tetanic fade, and posttetanic count), and the mechanomyogram are presented on screen continuously, are stored on floppy disk, and can be printed in a well-organized format.

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Year:  1993        PMID: 8385185     DOI: 10.1007/bf01627635

Source DB:  PubMed          Journal:  J Clin Monit        ISSN: 0748-1977


  25 in total

1.  A PORTABLE PERIPHERAL NERVE-STIMULATOR.

Authors:  H C CHURCHILL-DAVIDSON
Journal:  Anesthesiology       Date:  1965 Mar-Apr       Impact factor: 7.892

2.  COMPARISON OF ELECTRICAL AND MECHANICAL RECORDING OF SPONTANEOUS AND EVOKED MUSCLE ACTIVITY. THE CLINICAL VALUE OF CONTINUOUS RECORDING AS AN AID TO THE RATIONAL USE OF MUSCLE RELAXANTS DURING ANESTHESIA.

Authors:  R L KATZ
Journal:  Anesthesiology       Date:  1965 Mar-Apr       Impact factor: 7.892

3.  Proceedings: The effect of hypothermia on neuromuscular conduction.

Authors:  R J Thornton; C Blakeney; S A Feldman
Journal:  Br J Anaesth       Date:  1976-03       Impact factor: 9.166

4.  Twitch tension and train-of-four ratio during prolonged neuromuscular monitoring at different peripheral temperatures.

Authors:  L I Eriksson; C Lennmarken; E Jensen; J Viby-Mogensen
Journal:  Acta Anaesthesiol Scand       Date:  1991-04       Impact factor: 2.105

5.  The pharmacodynamics and pharmacokinetics of Org 9426, a new non-depolarizing neuromuscular blocking agent, in patients anaesthetized with nitrous oxide, halothane and fentanyl.

Authors:  J M Wierda; U W Kleef; L M Lambalk; W D Kloppenburg; S Agoston
Journal:  Can J Anaesth       Date:  1991-05       Impact factor: 5.063

6.  Monitoring of neuromuscular transmission in anesthetized man by a bulb-transducer assembly.

Authors:  A Baraka
Journal:  Anesth Analg       Date:  1973 Jan-Feb       Impact factor: 5.108

7.  The electromechanical response to stimulation by the Block-Aid Monitor.

Authors:  R A Epstein; S R Wyte; S H Jackson; S Sitter
Journal:  Anesthesiology       Date:  1969-01       Impact factor: 7.892

8.  A means of recording force of thumb adduction.

Authors:  L F Walts; M Lebowtiz; J B Dillon
Journal:  Anesthesiology       Date:  1968 Sep-Oct       Impact factor: 7.892

9.  A nerve stimulator for the continuous monitoring of muscle relaxant action.

Authors:  R L Katz
Journal:  Anesthesiology       Date:  1965 Nov-Dec       Impact factor: 7.892

10.  The effect of temperature, ischaemia and contractile activity on the relaxation rate of human muscle.

Authors:  C M Wiles; R H Edwards
Journal:  Clin Physiol       Date:  1982-12
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  7 in total

1.  Stabilization and stability of twitch force during mechanomyography of the adductor pollicis muscle.

Authors:  G van Santen; V Fidler; J M Wierda
Journal:  J Clin Monit Comput       Date:  1998-12       Impact factor: 2.502

2.  Mindray 3-directional NMT Module (a new generation "Tri-axial" neuromuscular monitor) versus the Relaxometer mechanomyograph and versus the TOF-Watch SX acceleromyograph.

Authors:  Ashraf A Dahaba; Ismet Suljevic; Zhao Yang Xiao; Kun Wang
Journal:  J Clin Monit Comput       Date:  2018-12-05       Impact factor: 2.502

3.  The effect of maintaining a constant preload or a constant degree of thumb abduction in the isometric twitch force of the thumb.

Authors:  G van Santen; E Otten; J M Wierda
Journal:  J Clin Monit Comput       Date:  1999-02       Impact factor: 2.502

4.  Increase in twitch force of the adductor pollicis muscle with stabilized preload at constant thumb abduction before and after administration of muscle relaxant.

Authors:  G van Santen; J M Wierda; V Fidler
Journal:  J Clin Monit Comput       Date:  1999-07       Impact factor: 2.502

5.  Clinical pharmacology of ORG 7617, a short-acting non-depolarizing neuromuscular blocking agent.

Authors:  L van den Broek; J M Wierda; J H Proost; F D Hommes; S Agoston
Journal:  Eur J Clin Pharmacol       Date:  1994       Impact factor: 2.953

6.  Preliminary investigations of the clinical pharmacology of three short-acting non-depolarizing neuromuscular blocking agents, Org 9453, Org 9489 and Org 9487.

Authors:  J M Wierda; A M Beaufort; U W Kleef; N J Smeulers; S Agoston
Journal:  Can J Anaesth       Date:  1994-03       Impact factor: 5.063

7.  The pharmacodynamics of rocuronium in pediatric patients anesthetized with halothane.

Authors:  G Bikhazi; F Marin; N J Halliday; K Deepika; F F Foldes
Journal:  J Anesth       Date:  1994-09       Impact factor: 2.078

  7 in total

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