Literature DB >> 8384999

Expression and localization of oxytocin receptor gene in human uterine endometrium in relation to the menstrual cycle.

M Takemura1, S Nomura, T Kimura, T Inoue, H Onoue, C Azuma, F Saji, Y Kitamura, O Tanizawa.   

Abstract

The expression of oxytocin receptor mRNA in the human uterus was investigated by polymerase chain reaction after mRNA reverse transcription; in addition, the mRNA was localized by means of in situ hybridization histochemistry. Strong positive signals were observed in myometrial cells at parturition. In nonpregnant human uterine endometrium, oxytocin receptor mRNA was expressed in glandular epithelial cells, but was not observed in stromal cells. The signal in the epithelial cells was stronger at the time of ovulation than during any other phase. The sequential changes in oxytocin receptor mRNA expression in nonpregnant endometrium suggest some alternative biological function of oxytocin in endometrium during the menstrual cycle.

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Year:  1993        PMID： 8384999     DOI： 10.1210/endo.132.4.8384999

Source DB:  PubMed          Journal:  Endocrinology        ISSN： 0013-7227            Impact factor:   4.736


  7 in total

1.  Side population in human uterine myometrium displays phenotypic and functional characteristics of myometrial stem cells.

Authors:  Masanori Ono; Tetsuo Maruyama; Hirotaka Masuda; Takashi Kajitani; Takashi Nagashima; Toru Arase; Mamoru Ito; Kuniaki Ohta; Hiroshi Uchida; Hironori Asada; Yasunori Yoshimura; Hideyuki Okano; Yumi Matsuzaki
Journal:  Proc Natl Acad Sci U S A       Date:  2007-11-14       Impact factor: 11.205

2.  Adenomyosis: Mechanisms and Pathogenesis.

Authors:  Junyu Zhai; Silvia Vannuccini; Felice Petraglia; Linda C Giudice
Journal:  Semin Reprod Med       Date:  2020-10-08       Impact factor: 1.303

3.  Immunolocalization and gene expression of oxytocin receptors in carcinomas and non-neoplastic tissues of the breast.

Authors:  G Bussolati; P Cassoni; G Ghisolfi; F Negro; A Sapino
Journal:  Am J Pathol       Date:  1996-06       Impact factor: 4.307

4.  Expression and localization of human oxytocin receptor mRNA and its protein in chorion and decidua during parturition.

Authors:  M Takemura; T Kimura; S Nomura; Y Makino; T Inoue; T Kikuchi; Y Kubota; Y Tokugawa; T Nobunaga; S Kamiura
Journal:  J Clin Invest       Date:  1994-06       Impact factor: 14.808

5.  Oxytocin inhibits proliferation of human breast cancer cell lines.

Authors:  P Cassoni; A Sapino; F Negro; G Bussolati
Journal:  Virchows Arch       Date:  1994       Impact factor: 4.064

6.  Adenomyosis and endometriosis. Re-visiting their association and further insights into the mechanisms of auto-traumatisation. An MRI study.

Authors:  G Leyendecker; A Bilgicyildirim; M Inacker; T Stalf; P Huppert; G Mall; B Böttcher; L Wildt
Journal:  Arch Gynecol Obstet       Date:  2014-09-21       Impact factor: 2.344

7.  Acquired contractile ability in human endometrial stromal cells by passive loading of cyclic tensile stretch.

Authors:  Jeonghyun Kim; Takashi Ushida; Kevin Montagne; Yasushi Hirota; Osamu Yoshino; Takehiro Hiraoka; Yutaka Osuga; Katsuko S Furuakwa
Journal:  Sci Rep       Date:  2020-06-02       Impact factor: 4.379
  7 in total

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