Literature DB >> 8383731

A new bastadin from the sponge Psammaplysilla purpurea.

J R Carney1, P J Scheuer, M Kelly-Borges.   

Abstract

A new bastadin 2 and the previously reported bastadins 5 [3], 7 [4], and 12 (formerly bastadin 9) [5] were isolated from the Verongid sponge Psammaplysilla purpurea collected in Pohnpei. Compound 2 is mildly cytotoxic against several cell lines and inhibits the enzymes topoisomerase II and dehydrofolate reductase.

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Year:  1993        PMID： 8383731     DOI： 10.1021/np50091a025

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  7 in total

Review 1.  The marine bromotyrosine derivatives.

Authors:  Jiangnan Peng; Jing Li; Mark T Hamann
Journal:  Alkaloids Chem Biol       Date:  2005

2.  Lithothamnin A, the first bastadin-like metabolite from the red alga Lithothamnion fragilissimum.

Authors:  Albert W W Van Wyk; Karina M Zuck; Tawnya C McKee
Journal:  J Nat Prod       Date:  2011-04-13       Impact factor: 4.050

3.  Simplified cyclic analogues of bastadin-5. Structure-activity relationships for modulation of the RyR1/FKBP12 Ca2+ channel complex.

Authors:  Makoto N Masuno; Isaac N Pessah; Marilyn M Olmstead; Tadeusz F Molinski
Journal:  J Med Chem       Date:  2006-07-27       Impact factor: 7.446

4.  Antifouling activity of bromotyrosine-derived sponge metabolites and synthetic analogues.

Authors:  Sofia Ortlepp; Martin Sjögren; Mia Dahlström; Horst Weber; Rainer Ebel; RuAngelie Edrada; Carsten Thoms; Peter Schupp; Lars Bohlin; Peter Proksch
Journal:  Mar Biotechnol (NY)       Date:  2007-08-23       Impact factor: 3.619

5.  FBA-TPQ, a novel marine-derived compound as experimental therapy for prostate cancer.

Authors:  Feng Wang; Scharri J Ezell; Yong Zhang; Wei Wang; Elizabeth R Rayburn; Dwayaja H Nadkarni; Srinivasan Murugesan; Sadanandan E Velu; Ruiwen Zhang
Journal:  Invest New Drugs       Date:  2009-03-10       Impact factor: 3.850

6.  Additional insights on the bastadins: isolation of analogues from the sponge Ianthella cf. reticulata and exploration of the oxime configurations.

Authors:  Laurent Calcul; Wayne D Inman; Alexi A Morris; Karen Tenney; Joseline Ratnam; James H McKerrow; Frederick A Valeriote; Phillip Crews
Journal:  J Nat Prod       Date:  2010-03-26       Impact factor: 4.050

Review 7.  A journey under the sea: the quest for marine anti-cancer alkaloids.

Authors:  Rita Tohme; Nadine Darwiche; Hala Gali-Muhtasib
Journal:  Molecules       Date:  2011-11-23       Impact factor: 4.411
  7 in total

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