| Literature DB >> 8382447 |
E Weinberg1, S Hoisington, A Y Eastman, D K Rice, J Malfetano, J S Ross.
Abstract
A poorly differentiated squamous cell carcinoma of the cervix with marked lymphoplasmacytic stromal infiltration is described in a 21-year-old black woman who had postcoital bleeding. Histologic features were strikingly similar to the classic lymphoepithelioma of the nasopharynx. Serologic evidence for remote Epstein-Barr virus infection was present. However, polymerase chain reaction amplification and hybridization of DNA extracted from fresh-frozen tumor tissue failed to identify Epstein-Barr virus genomic DNA. No human papillomavirus DNA was detected by polymerase chain reaction amplification. The histologic and Epstein-Barr virus results of the uterine cervical lymphoepitheliomal-like carcinoma were compared to the classic nasopharyngeal lymphoepithelioma and to similar tumors studied from other anatomic sites.Entities:
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Year: 1993 PMID: 8382447 DOI: 10.1093/ajcp/99.2.195
Source DB: PubMed Journal: Am J Clin Pathol ISSN: 0002-9173 Impact factor: 2.493