Literature DB >> 8381806

Persistence of intestinal antibody response to heterologous rotavirus infection in a murine model beyond 1 year.

R D Shaw1, A A Merchant, W S Groene, E H Cheng.   

Abstract

We used an ELISPOT (enzyme-linked immunosorbent spot) assay to quantitate the long-term rotavirus-specific intestinal antibody response in a murine model. The frequency of murine intestinal antibody-secreting cells (ASCs) was followed for a period of 1 year after a single dose of rhesus rotavirus (10(6) PFU) was administered at 10 days of age. Some animals were boosted at that time with a second dose. One year after infection, virus-specific ASCs declined from acute-phase levels, but they were still present at significant levels (1.32 x 10(4) virus-specific ASCs per 10(6) intestinal mononuclear cells; approximately 17% of the previously reported response at 1 month after infection). A booster dose 1 year after the primary infection produced a 100% increase in virus-specific ASCs but did not restore the response to that of the primary infection.

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Year:  1993        PMID： 8381806      PMCID： PMC262733          DOI： 10.1128/jcm.31.2.188-191.1993

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  10 in total

1.  A B cell population that dominates the primary response to influenza virus hemagglutinin does not participate in the memory response.

Authors:  J Kavaler; A J Caton; L M Staudt; W Gerhard
Journal:  Eur J Immunol       Date:  1991-11       Impact factor: 5.532

2.  Specific enzyme-linked immunoassay for rotavirus serotypes 1 and 3.

Authors:  R D Shaw; D L Stoner-Ma; M K Estes; H B Greenberg
Journal:  J Clin Microbiol       Date:  1985-08       Impact factor: 5.948

Review 3.  The adaptive potential of the memory response: clonal recruitment and epitope recognition.

Authors:  M P Stenzel-Poore; U Bruderer; M B Rittenberg
Journal:  Immunol Rev       Date:  1988-10       Impact factor: 12.988

Review 4.  Mutation drift and repertoire shift in the maturation of the immune response.

Authors:  C Berek; C Milstein
Journal:  Immunol Rev       Date:  1987-04       Impact factor: 12.988

5.  Analysis of somatic mutation and class switching in naive and memory B cells generating adoptive primary and secondary responses.

Authors:  M Siekevitz; C Kocks; K Rajewsky; R Dildrop
Journal:  Cell       Date:  1987-03-13       Impact factor: 41.582

6.  VP4-specific intestinal antibody response to rotavirus in a murine model of heterotypic infection.

Authors:  R D Shaw; W S Groene; E R Mackow; A A Merchant; E H Cheng
Journal:  J Virol       Date:  1991-06       Impact factor: 5.103

7.  Murine intestinal antibody response to heterologous rotavirus infection.

Authors:  A A Merchant; W S Groene; E H Cheng; R D Shaw
Journal:  J Clin Microbiol       Date:  1991-08       Impact factor: 5.948

8.  Distribution of rotavirus antigen in intestinal lymphoid tissues: potential role in development of the mucosal immune response to rotavirus.

Authors:  T Dharakul; M Riepenhoff-Talty; B Albini; P L Ogra
Journal:  Clin Exp Immunol       Date:  1988-10       Impact factor: 4.330

9.  Long-term cholera antitoxin memory in the gut can be triggered to antibody formation associated with protection within hours of an oral challenge immunization.

Authors:  N Lycke; J Holmgren
Journal:  Scand J Immunol       Date:  1987-04       Impact factor: 3.487

10.  Antigenic mapping of the surface proteins of rhesus rotavirus.

Authors:  R D Shaw; P T Vo; P A Offit; B S Coulson; H B Greenberg
Journal:  Virology       Date:  1986-12       Impact factor: 3.616
  10 in total
  8 in total

1.  Systematic and intestinal antibody-secreting cell responses and correlates of protective immunity to human rotavirus in a gnotobiotic pig model of disease.

Authors:  L Yuan; L A Ward; B I Rosen; T L To; L J Saif
Journal:  J Virol       Date:  1996-05       Impact factor: 5.103

2.  Protection of the villus epithelial cells of the small intestine from rotavirus infection does not require immunoglobulin A.

Authors:  C M O'Neal; G R Harriman; M E Conner
Journal:  J Virol       Date:  2000-05       Impact factor: 5.103

3.  Commensal enteric bacteria engender a self-limiting humoral mucosal immune response while permanently colonizing the gut.

Authors:  K E Shroff; K Meslin; J J Cebra
Journal:  Infect Immun       Date:  1995-10       Impact factor: 3.441

4.  Serum IgA immune response to individual rotavirus polypeptides in young children with rotavirus infection.

Authors:  K Johansen; L Granqvist; K Karlén; G Stintzing; I Uhnoo; L Svensson
Journal:  Arch Virol       Date:  1994       Impact factor: 2.574

5.  Rotavirus-specific intestinal immune response in mice assessed by enzyme-linked immunospot assay and intestinal fragment culture.

Authors:  C A Khoury; K A Brown; J E Kim; P A Offit
Journal:  Clin Diagn Lab Immunol       Date:  1994-11

6.  Relative importance of rotavirus-specific effector and memory B cells in protection against challenge.

Authors:  C A Moser; S Cookinham; S E Coffin; H F Clark; P A Offit
Journal:  J Virol       Date:  1998-02       Impact factor: 5.103

7.  Short-term immunoglobulin A B-cell memory resides in intestinal lymphoid tissues but not in bone marrow of gnotobiotic pigs inoculated with Wa human rotavirus.

Authors:  L Yuan; A Geyer; L J Saif
Journal:  Immunology       Date:  2001-06       Impact factor: 7.397

Review 8.  Rotaviruses: immunological determinants of protection against infection and disease.

Authors:  P A Offit
Journal:  Adv Virus Res       Date:  1994       Impact factor: 9.937
  8 in total

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