Literature DB >> 8381323

Myeloperoxidase deficiency in a patient with rheumatoid arthritis: oxygenation and radical activity by phagocytic cells.

A L Bell1, G M Markey, H D Alexander, T C Morris, S A McMillan, J A McNally.   

Abstract

Complete functional deficiency of the phagocytic cell enzyme, myeloperoxidase, is described in a patient with rheumatoid arthritis. Measurement of oxygenation and free radical activity by blood monocytes and polymorphonuclear leucocytes shows gross reduction in myeloperoxidase-dependent chemiluminescence. Implications of these data for theories linking reactive oxygen species to inflammatory tissue damage in rheumatoid arthritis are discussed.

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Year:  1993        PMID: 8381323     DOI: 10.1093/rheumatology/32.2.162

Source DB:  PubMed          Journal:  Br J Rheumatol        ISSN: 0263-7103


  2 in total

1.  Allelic polymorphism in IL-1 beta and IL-1 receptor antagonist (IL-1Ra) genes in inflammatory bowel disease.

Authors:  G Bioque; J B Crusius; I Koutroubakis; G Bouma; P J Kostense; S G Meuwissen; A S Peña
Journal:  Clin Exp Immunol       Date:  1995-11       Impact factor: 4.330

2.  Upregulation of expression of the chemokine receptor CCR5 by hydrogen peroxide in human monocytes.

Authors:  Geneviève Lehoux; Christian Le Gouill; Jana Stankova; Marek Rola-Pleszczynski
Journal:  Mediators Inflamm       Date:  2003-02       Impact factor: 4.711

  2 in total

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