| Literature DB >> 8381323 |
A L Bell1, G M Markey, H D Alexander, T C Morris, S A McMillan, J A McNally.
Abstract
Complete functional deficiency of the phagocytic cell enzyme, myeloperoxidase, is described in a patient with rheumatoid arthritis. Measurement of oxygenation and free radical activity by blood monocytes and polymorphonuclear leucocytes shows gross reduction in myeloperoxidase-dependent chemiluminescence. Implications of these data for theories linking reactive oxygen species to inflammatory tissue damage in rheumatoid arthritis are discussed.Entities:
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Year: 1993 PMID: 8381323 DOI: 10.1093/rheumatology/32.2.162
Source DB: PubMed Journal: Br J Rheumatol ISSN: 0263-7103