J A Carlson1, B L Ackerman, J E Wheeler. 1. Department of Obstetrics and Gynecology, Hospital of the University of Pennsylvania, Philadelphia.
Abstract
BACKGROUND: Malignant mixed müllerian tumor (MMT) of tubal origin is rare and optimal therapy is unknown. METHODS: Five new cases of MMT of the fallopian tube are presented, and the previous literature is reviewed. RESULTS: Eight of 10 patients disease-free at 36 months had long-term cancer-free survival. Surgery alone was inadequate therapy even for those with apparent Stage I disease. Five of six treated postoperatively with radiation and chemotherapy have lived disease-free for at least 45 months. CONCLUSIONS: Combination radiation and chemotherapy may offer improved outcome.
BACKGROUND: Malignant mixed müllerian tumor (MMT) of tubal origin is rare and optimal therapy is unknown. METHODS: Five new cases of MMT of the fallopian tube are presented, and the previous literature is reviewed. RESULTS: Eight of 10 patients disease-free at 36 months had long-term cancer-free survival. Surgery alone was inadequate therapy even for those with apparent Stage I disease. Five of six treated postoperatively with radiation and chemotherapy have lived disease-free for at least 45 months. CONCLUSIONS: Combination radiation and chemotherapy may offer improved outcome.
Authors: Alexandra Lavinia Cozlea; Mihai Gheorghe; Szilard Leo Kiss; Anas Fandi; Mihai Stanca; Simona Mocan; Mihai Emil Căpîlna; Nicolae Bacalbașa; Andreea Anamaria Moldovan Journal: Exp Ther Med Date: 2021-12-28 Impact factor: 2.447