Literature DB >> 8379450

Metabolic effects of inhibiting glucosylceramide synthesis with PDMP and other substances.

N S Radin1, J A Shayman, J Inokuchi.   

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Year:  1993        PMID: 8379450

Source DB:  PubMed          Journal:  Adv Lipid Res        ISSN: 0065-2849


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  29 in total

1.  Adamantyl glycosphingolipids provide a new approach to the selective regulation of cellular glycosphingolipid metabolism.

Authors:  Mustafa Kamani; Murugesapillai Mylvaganam; Robert Tian; Brigitte Rigat; Beth Binnington; Clifford Lingwood
Journal:  J Biol Chem       Date:  2011-04-25       Impact factor: 5.157

2.  1-phenyl-2-decanoylamino-3-morpholino-1-propanol (PDMP) facilitates curcumin-induced melanoma cell apoptosis by enhancing ceramide accumulation, JNK activation, and inhibiting PI3K/AKT activation.

Authors:  Teng Yu; Jinchao Li; Ying Qiu; Hui Sun
Journal:  Mol Cell Biochem       Date:  2011-09-29       Impact factor: 3.396

3.  3'-Azidothymidine significantly alters glycosphingolipid synthesis in melanoma cells and decreases the shedding of gangliosides.

Authors:  R Steet; M Alizadeh; P Melançon; R D Kuchta
Journal:  Glycoconj J       Date:  1999-03       Impact factor: 2.916

Review 4.  Remodeling of sphingolipids by plasma membrane associated enzymes.

Authors:  Massimo Aureli; Nicoletta Loberto; Vanna Chigorno; Alessandro Prinetti; Sandro Sonnino
Journal:  Neurochem Res       Date:  2010-12-23       Impact factor: 3.996

5.  Histidine-193 of rat glucosylceramide synthase resides in a UDP-glucose- and inhibitor (D-threo-1-phenyl-2-decanoylamino-3-morpholinopropan-1-ol)-binding region: a biochemical and mutational study.

Authors:  K Wu; D L Marks; R Watanabe; P Paul; N Rajan; R E Pagano
Journal:  Biochem J       Date:  1999-07-15       Impact factor: 3.857

6.  Glycosphingolipid deficiency affects functional microdomain formation in Lewis lung carcinoma cells.

Authors:  J I Inokuchi; S Uemura; K Kabayama; Y Igarashi
Journal:  Glycoconj J       Date:  2000 Mar-Apr       Impact factor: 2.916

7.  DNA damage induces down-regulation of UDP-glucose ceramide glucosyltransferase, increases ceramide levels and triggers apoptosis in p53-deficient cancer cells.

Authors:  Teka-Ann S Haynes; Valery Filippov; Maria Filippova; Jun Yang; Kangling Zhang; Penelope J Duerksen-Hughes
Journal:  Biochim Biophys Acta       Date:  2012-02-11

8.  Effects of gangliosides on the activity of the plasma membrane Ca2+-ATPase.

Authors:  Lei Jiang; Misty D Bechtel; Jennifer L Bean; Robert Winefield; Todd D Williams; Asma Zaidi; Elias K Michaelis; Mary L Michaelis
Journal:  Biochim Biophys Acta       Date:  2014-01-14

9.  Prognostic relevance of glucosylceramide synthase (GCS) expression in breast cancer.

Authors:  Eugen Ruckhäberle; Thomas Karn; Lars Hanker; Regine Gätje; Dirk Metzler; Uwe Holtrich; Manfred Kaufmann; Achim Rody
Journal:  J Cancer Res Clin Oncol       Date:  2008-06-17       Impact factor: 4.553

10.  VEGF recruits lactosylceramide to induce endothelial cell adhesion molecule expression and angiogenesis in vitro and in vivo.

Authors:  Antonina Kolmakova; Mohanraj Rajesh; David Zang; Roberto Pili; Subroto Chatterjee
Journal:  Glycoconj J       Date:  2009-02-14       Impact factor: 2.916

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