Literature DB >> 8378652

[Bone metastases of colorectal cancers: apropos of 8 cases].

R Delva1, F Pein, A Lortholary, E Gamelin, P Cellier, F Larra.   

Abstract

Having found, in the same medical centre, an abnormally high (15%) frequency of bone metastases from colorectal carcinoma, the authors report a series of 8 cases and review what is now known of this reputed rare (4%) metastases. Their clinical and imaging features are not very different from secondary bone lesions of other origins. They usually appear approximately 5 years after the primary tumour has been diagnosed; and they are rarely isolated, being part of a diffuse metastatic disease; their prognosis is in fact conditioned by visceral metastases (liver, lung, peritoneum). Concerning treatment, pain relieving radiotherapy is crucial, as witnesses by the authors. Chemotherapy must always be prescribed for its proven effectiveness against visceral lesions. The other medicinal treatments (e.g. analgesics, bisphosphonates) are very useful. Surgery must be reserved to emergency situations (spinal cord compression) and to patients in good general condition. To our 8 patients these treatments brought comfort and increased survival. Survivals of at least 6 to 9 months were obtained, and one patient is still alive 14 months after the diagnosis of bone metastasis. These results compare favourably with the 4 months median survival observed in other series.

Entities:  

Mesh:

Year:  1993        PMID: 8378652     DOI: 10.1016/s0248-8663(05)82487-7

Source DB:  PubMed          Journal:  Rev Med Interne        ISSN: 0248-8663            Impact factor:   0.728


  5 in total

1.  Prognostic risk factors in patients with bone metastasis from colorectal cancer.

Authors:  Fangqi Liu; Jiang Zhao; Jie Xie; Li Xie; Ji Zhu; Sanjun Cai; Hongtu Zheng; Ye Xu
Journal:  Tumour Biol       Date:  2016-10-12

2.  Long-term disease-free survival after surgical resection for multiple bone metastases from rectal cancer.

Authors:  Seok Jin Choi; Jong Hun Kim; Min Ro Lee; Chang Ho Lee; Ja Hong Kuh; Jung Ryul Kim
Journal:  World J Clin Oncol       Date:  2011-08-10

Review 3.  Metastatic colorectal cancer presenting with bone marrow metastasis: a case series and review of literature.

Authors:  Rita Assi; Deborah Mukherji; Ali Haydar; Maya Saroufim; Sally Temraz; Ali Shamseddine
Journal:  J Gastrointest Oncol       Date:  2016-04

Review 4.  [Brain metastasis from rectal adenocarcinoma: about a case and review of the literature].

Authors:  Hamza Samlali; Zineb Bouchbika; Zineb Bennani; Amina Taleb; Nadia Benchekroune; Hassan Jouhadi; Nezha Tawfiq; Souha Sahraoui; Abdellatif Benider
Journal:  Pan Afr Med J       Date:  2017-02-01

5.  Bone Metastasis As the Initial Presentation of a Hidden Bronchogenic Carcinoma.

Authors:  Anas Ibraheem
Journal:  Cureus       Date:  2022-08-16
  5 in total

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