Literature DB >> 8377530

Have human biological functions evolved in support of a life-span?

R A Weale1.   

Abstract

Published data on age-related human biological functions are surveyed. For the many showing a linear decrease, regressions were calculated, or existing functions extrapolated, to yield an intercept on the abscissa. The values of chi(0), the age at which a function ceases, provide a tentative common means of comparison. The distribution of chi(0) is skewed because of the apparent longevity of nervous and cerebral functions. The database is sufficiently large to enable one to distinguish those biological functions which appear to have immediate survival value from those which do not. Such an approach may link biomarkers to estimates of the life-span of species.

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Year:  1993        PMID: 8377530     DOI: 10.1016/0047-6374(93)90072-y

Source DB:  PubMed          Journal:  Mech Ageing Dev        ISSN: 0047-6374            Impact factor:   5.432


  1 in total

Review 1.  Does senescence give rise to disease?

Authors:  Bruce A Carnes; David O Staats; William E Sonntag
Journal:  Mech Ageing Dev       Date:  2008-10-10       Impact factor: 5.432

  1 in total

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