| Literature DB >> 8376486 |
C P Babalola1, O O Bolaji, P A Dixon, F A Ogunbona.
Abstract
A new simple, selective and reproducible high-performance liquid chromatographic method for the determination of quinine in plasma, saliva and urine is described. The ion-pair method was carried out on a reversed-phase C18 column, using perchlorate ion as the counter ion and ultraviolet detection at 254 nm. Quinine was well resolved from its major metabolite, 3-hydroxyquinine, and the internal standard, primaquine. The limit of detection was 10 ng/ml and the recovery was greater than 90% from the three biological fluids.Entities:
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Year: 1993 PMID： 8376486 DOI： 10.1016/0378-4347(93)80482-j
Source DB: PubMed Journal: J Chromatogr