Literature DB >> 8375501

Immunohistochemical analysis of rat S-adenosylmethionine synthetase isozymes in developmental liver.

S Horikawa1, H Ozasa, K Ota, K Tsukada.   

Abstract

Mammalian S-adenosylmethionine (AdoMet) synthetase exists as two isozymes, liver-type and kidney(non-hepatic)-type enzymes. The developmental expression of these two isozymes proteins has been investigated in rat liver using immunohistochemical techniques. The liver-type AdoMet synthetase is expressed only in adult liver, but not in fetal liver. On the other hand, the kidney-type AdoMet synthetase is predominantly expressed in fetal liver and faintly detected in adult liver. It was also found that both isozymes were localized to the hepatocytes of rat liver. These results clearly show that AdoMet synthetase isozymes are developmentally regulated within hepatocytes. In addition, in rat kidney we have shown that the kidney-type AdoMet synthetase is predominantly localized to the distal tubule.

Entities:  

Mesh：

Substances：

Year:  1993        PMID： 8375501     DOI： 10.1016/0014-5793(93)80894-z

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  12 in total

1.  Proteomic analysis of human hepatoma cells expressing methionine adenosyltransferase I/III: Characterization of DDX3X as a target of S-adenosylmethionine.

Authors:  Paul C Schröder; Joaquín Fernández-Irigoyen; Emilie Bigaud; Antonio Serna; Rubén Renández-Alcoceba; Shelly C Lu; José M Mato; Jesús Prieto; Fernando J Corrales
Journal:  J Proteomics       Date:  2012-01-16       Impact factor: 4.044

2.  Methionine adenosyltransferase 1A knockout mice are predisposed to liver injury and exhibit increased expression of genes involved in proliferation.

Authors:  S C Lu; L Alvarez; Z Z Huang; L Chen; W An; F J Corrales; M A Avila; G Kanel; J M Mato
Journal:  Proc Natl Acad Sci U S A       Date:  2001-04-24       Impact factor: 11.205

3.  Inhibition of human methionine adenosyltransferase 1A transcription by coding region methylation.

Authors:  Maria Lauda Tomasi; Tony W H Li; Mei Li; José M Mato; Shelly C Lu
Journal:  J Cell Physiol       Date:  2012-04       Impact factor: 6.384

4.  Correlation between the expression of methionine adenosyltransferase and the stages of human colorectal carcinoma.

Authors:  K Ito; S Ikeda; N Kojima; M Miura; K Shimizu-Saito; I Yamaguchi; I Katsuyama; K Sanada; T Iwai; H Senoo; S Horikawa
Journal:  Surg Today       Date:  2000       Impact factor: 2.549

Review 5.  Metabolism of sulfur amino acids in Saccharomyces cerevisiae.

Authors:  D Thomas; Y Surdin-Kerjan
Journal:  Microbiol Mol Biol Rev       Date:  1997-12       Impact factor: 11.056

6.  Cloning and functional characterization of the 5'-flanking region of human methionine adenosyltransferase 1A gene.

Authors:  Z Zeng; Z Z Huang; C Chen; H Yang; Z Mao; S C Lu
Journal:  Biochem J       Date:  2000-03-01       Impact factor: 3.857

7.  The role of c-Myb in the up-regulation of methionine adenosyltransferase 2A expression in activated Jurkat cells.

Authors:  Z Zeng; H Yang; Z Z Huang; C Chen; J Wang; S C Lu
Journal:  Biochem J       Date:  2001-01-01       Impact factor: 3.857

Review 8.  S-adenosylmethionine in liver health, injury, and cancer.

Authors:  Shelly C Lu; José M Mato
Journal:  Physiol Rev       Date:  2012-10       Impact factor: 37.312

9.  Lentivirus mediated shRNA interference targeting MAT2B induces growth-inhibition and apoptosis in hepatocelluar carcinoma.

Authors:  Qun Wang; Quan-Yan Liu; Zhi-Su Liu; Qun Qian; Quan Sun; Ding-Yu Pan
Journal:  World J Gastroenterol       Date:  2008-08-07       Impact factor: 5.742

Review 10.  S-Adenosylmethionine in cell growth, apoptosis and liver cancer.

Authors:  Shelly C Lu; José M Mato
Journal:  J Gastroenterol Hepatol       Date:  2008-03       Impact factor: 4.029
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.