Literature DB >> 8375486

Trichuris suis: a zinc metalloprotease from culture fluids of adult parasites.

D E Hill1, H R Gamble, M L Rhoads, R H Fetterer, J F Urban.   

Abstract

A zinc metalloendoprotease has been isolated from in vitro culture fluids of Trichuris suis adults. The protease was purified from total culture fluids by passage through a cation exchange high-pressure liquid chromatography column. The 45-kDa protease has a pH optimum of 7.0 and an isoelectric point of 8.0 and was localized to the stichosome of the parasites using immunohistochemistry techniques.

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Year:  1993        PMID： 8375486     DOI： 10.1006/expr.1993.1074

Source DB:  PubMed          Journal:  Exp Parasitol        ISSN： 0014-4894            Impact factor:   2.011


  8 in total

1.  Matrix metalloproteinases activity demonstrated in the infective stage of the nematodes, Angiostrongylus cantonensis.

Authors:  S C Lai; S T Jiang; K M Chen; H H Lee
Journal:  Parasitol Res       Date:  2005-09-16       Impact factor: 2.289

2.  Alterations in the porcine colon microbiota induced by the gastrointestinal nematode Trichuris suis.

Authors:  Robert W Li; Sitao Wu; Weizhong Li; Karl Navarro; Robin D Couch; Dolores Hill; Joseph F Urban
Journal:  Infect Immun       Date:  2012-04-09       Impact factor: 3.441

3.  Characterization and cloning of metallo-proteinase in the excretory/secretory products of the infective-stage larva of Trichinella spiralis.

Authors:  H M Lun; C H Mak; R C Ko
Journal:  Parasitol Res       Date:  2003-01-28       Impact factor: 2.289

4.  The transcriptome of Trichuris suis--first molecular insights into a parasite with curative properties for key immune diseases of humans.

Authors:  Cinzia Cantacessi; Neil D Young; Peter Nejsum; Aaron R Jex; Bronwyn E Campbell; Ross S Hall; Stig M Thamsborg; Jean-Pierre Scheerlinck; Robin B Gasser
Journal:  PLoS One       Date:  2011-08-24       Impact factor: 3.240

5.  Early exposure of infants to GI nematodes induces Th2 dominant immune responses which are unaffected by periodic anthelminthic treatment.

Authors:  Victoria J Wright; Shaali Makame Ame; Haji Said Haji; Rosemary E Weir; David Goodman; David I Pritchard; Mahdi Ramsan Mohamed; Hamad Juma Haji; James M Tielsch; Rebecca J Stoltzfus; Quentin D Bickle
Journal:  PLoS Negl Trop Dis       Date:  2009-05-19

6.  Serine protease(s) secreted by the nematode Trichuris muris degrade the mucus barrier.

Authors:  Sumaira Z Hasnain; Michael A McGuckin; Richard K Grencis; David J Thornton
Journal:  PLoS Negl Trop Dis       Date:  2012-10-11

Review 7.  Enzymology of the nematode cuticle: A potential drug target?

Authors:  Antony P Page; Gillian Stepek; Alan D Winter; David Pertab
Journal:  Int J Parasitol Drugs Drug Resist       Date:  2014-06-06       Impact factor: 4.077

8.  Pathway of oxfendazole from the host into the worm: Trichuris suis in pigs.

Authors:  Tina V A Hansen; Andrew R Williams; Matthew Denwood; Peter Nejsum; Stig M Thamsborg; Christian Friis
Journal:  Int J Parasitol Drugs Drug Resist       Date:  2017-11-09       Impact factor: 4.077
  8 in total

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