Literature DB >> 8374993

Two new 2-arylbenzofuran derivatives from hypoglycemic activity-bearing fractions of Morus insignis.

P Basnet1, S Kadota, S Terashima, T Namba.   

Abstract

Ethyl acetate- and n-butanol-soluble fractions of the leaves of Morus insignis showed a significant hypoglycemic activity on streptozotocin (STZ)-induced hyperglycemic rats. From these hypoglycemic activity-showing fractions, two new compounds, mulberrofuran U (2) and moracin M-3-O-beta-D-glucopyranoside (3) were isolated, along with six known compounds [beta-sitosterol, beta-sitosterol-3-O-beta-glucopyranoside, ursolic acid, moracin M (1), kaempferol-3-O-beta-glucopyranoside and quercetin-3-O-beta-glucopyranoside] and the structures of the new compounds were determined by spectroscopic and chemical methods.

Entities:  

Mesh：

Substances：

Year:  1993        PMID： 8374993     DOI： 10.1248/cpb.41.1238

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


  9 in total

1.  Bioactive constituents from the roots of Panax japonicus var. major and development of a LC-MS/MS method for distinguishing between natural and artifactual compounds.

Authors:  Hsiu-Hui Chan; Tsong-Long Hwang; Mopur Vijaya Bhaskar Reddy; Ding-Tzai Li; Keduo Qian; Kenneth F Bastow; Kuo-Hsiung Lee; Tian-Shung Wu
Journal:  J Nat Prod       Date:  2011-03-18       Impact factor: 4.050

Review 2.  Antidiabetic phytoconstituents and their mode of action on metabolic pathways.

Authors:  Sudhanshu Kumar Bharti; Supriya Krishnan; Ashwini Kumar; Awanish Kumar
Journal:  Ther Adv Endocrinol Metab       Date:  2018-02-12       Impact factor: 3.565

Review 3.  Mulberry Diels-Alder-type adducts: isolation, structure, bioactivity, and synthesis.

Authors:  Si-Yuan Luo; Jun-Yu Zhu; Ming-Feng Zou; Sheng Yin; Gui-Hua Tang
Journal:  Nat Prod Bioprospect       Date:  2022-09-02

4.  Inhibition Mechanism of Components Isolated from Morus alba Branches on Diabetes and Diabetic Complications via Experimental and Molecular Docking Analyses.

Authors:  Ryeong-Ha Kwon; Niha Thaku; Binod Timalsina; Se-Eun Park; Jae-Sue Choi; Hyun-Ah Jung
Journal:  Antioxidants (Basel)       Date:  2022-02-14

5.  Inhibitory effects of constituents from Morus alba var. multicaulis on differentiation of 3T3-L1 cells and nitric oxide production in RAW264.7 cells.

Authors:  Zhi-Gang Yang; Keiichi Matsuzaki; Satoshi Takamatsu; Susumu Kitanaka
Journal:  Molecules       Date:  2011-07-19       Impact factor: 4.411

6.  Chlorogenic acid and rutin play a major role in the in vivo anti-diabetic activity of Morus alba leaf extract on type II diabetic rats.

Authors:  Attila Hunyadi; Ana Martins; Tusty-Jiuan Hsieh; Adrienn Seres; István Zupkó
Journal:  PLoS One       Date:  2012-11-21       Impact factor: 3.240

7.  Identification of Anti-Melanogenesis Constituents from Morus alba L. Leaves.

Authors:  Hong Xu Li; Jung Up Park; Xiang Dong Su; Kyung Tae Kim; Jong Seong Kang; Young Ran Kim; Young Ho Kim; Seo Young Yang
Journal:  Molecules       Date:  2018-10-08       Impact factor: 4.411

8.  Coumarin and Moracin Derivatives from Mulberry Leaves (Morus alba L.) with Soluble Epoxide Hydrolase Inhibitory Activity.

Authors:  Hong Xu Li; Myungsook Heo; Younghoon Go; Young Soo Kim; Young Ho Kim; Seo Young Yang; Wei Li
Journal:  Molecules       Date:  2020-08-31       Impact factor: 4.411

9.  Synthesis and biological evaluation of 2-arylbenzofuran derivatives as potential anti-Alzheimer's disease agents.

Authors:  Yinling Yun; Yuhang Miao; Xiaoya Sun; Jie Sun; Xiaojing Wang
Journal:  J Enzyme Inhib Med Chem       Date:  2021-12       Impact factor: 5.051
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.