Literature DB >> 8372604

Twin genes and endocrine disease: CYP21 and CYP11B genes.

A Helmberg1.   

Abstract

CYP21 and CYP11B genes have a common feature: they are "twin" genes. It seems as if doubling and subsequent drifting apart rendered these genes particularly sensitive to defect acquisition by mechanisms involving recombinatorial events. This creates specific difficulties in the molecular diagnosis of defects.

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Year:  1993        PMID： 8372604     DOI： 10.1530/acta.0.1290097

Source DB:  PubMed          Journal:  Acta Endocrinol (Copenh)        ISSN： 0001-5598


  4 in total

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2.  Genetic and mutational heterogeneity of autosomal recessive chronic granulomatous disease in Tunisia.

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3.  Analysis of steroid 21-hydroxylase gene mutations in the Spanish population.

Authors:  B Ezquieta; A Oliver; R Gracia; P G Gancedo
Journal:  Hum Genet       Date:  1995-08       Impact factor: 4.132

4.  Association between the CYP11 family and six cancer types.

Authors:  Ziwei Fan; Zhen Wang; Weiran Chen; Zhiwei Cao; Yixue Li
Journal:  Oncol Lett       Date:  2016-05-13       Impact factor: 2.967
  4 in total

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