Literature DB >> 8372151

Antidiarrhoeic activity of Euphorbia hirta extract and isolation of an active flavonoid constituent.

J Galvez1, A Zarzuelo, M E Crespo, M D Lorente, M A Ocete, J Jiménez.   

Abstract

The antidiarrhoeic activity of the Euphorbia hirta whole plant was investigated. The lyophilized decoction demonstrated antidiarrhoeic activity in experimental models of diarrhoea induced by castor oil, arachidonic acid, and prostaglandin E2. It showed no activity when magnesium sulphate was used to provoke the diarrhoea. The lyophilized decoction delayed small intestinal transit when this was accelerated by castor oil but not in normal conditions. A flavonoid, quercitrin, with antidiarrhoeic activity was isolated from this crude drug.

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Year:  1993        PMID： 8372151     DOI： 10.1055/s-2006-959694

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  40 in total

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Authors:  S Brijesh; P G Daswani; P Tetali; S R Rojatkar; N H Antia; T J Birdi
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7.  Anti-diarrheal activity of the leaf extracts of Daniellia oliveri Hutch and Dalz (Fabaceae) and Ficus sycomorus Miq (Moraceae).

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8.  Antidiarrhoeal activity of an ethanol extract of the stem bark of Piliostigma reticulatum (Caesalpiniaceae) in rats.

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9.  Euphorbia hirta reverses chronic stress-induced anxiety and mediates its action through the GABA(A) receptor benzodiazepine receptor-Cl(-) channel complex.

Authors:  H Anuradha; B N Srikumar; B S Shankaranarayana Rao; M Lakshmana
Journal:  J Neural Transm (Vienna)       Date:  2007-12-18       Impact factor: 3.575

10.  Studies on the antidiarrhoeal activity of Aegle marmelos unripe fruit: validating its traditional usage.

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Journal:  BMC Complement Altern Med       Date:  2009-11-23       Impact factor: 3.659
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