Literature DB >> 8372145

Free radical scavenger and antihepatotoxic activity of Rosmarinus tomentosus.

M Concepción Navarro1, M Pilar Montilla, A Martín, J Jiménez, M Pilar Utrilla.   

Abstract

The free radical scavenger and antihepatotoxic activity from Rosmarinus tomentosus ethanolic extract and its fractions were studied, and also its membrane stabilizing activity in rat erythrocytes. Pretreatment with an ethanolic extract of R. tomentosus caused an important decrease in the CCl4-induced toxicity in rats liver, made evident by its effect on the levels of GPT and bilirubin in the serum and the malondialdehyde (MDA) concentration in the liver. These effects are similar to those produced by silymarin. The chloroformic fraction showed the greatest antihepatotoxic activity and the ethyl acetate fraction the greatest free radical scavenger activity.

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Year:  1993        PMID： 8372145     DOI： 10.1055/s-2006-959688

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  42 in total

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5.  The hepatoprotective effect of coumarin and coumarin derivates on carbon tetrachloride-induced hepatic injury by antioxidative activities in rats.

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7.  Vanadyl sulfate administration protects the streptozotocin-induced oxidative damage to brain tissue in rats.

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Authors:  Sneha S Pillai; S Mini
Journal:  Plant Foods Hum Nutr       Date:  2016-03       Impact factor: 3.921

10.  Free Radical Scavenging Activity of Leaves of Alocasia indica (Linn).

Authors:  W A Mulla; V R Salunkhe; S B Kuchekar; M N Qureshi
Journal:  Indian J Pharm Sci       Date:  2009-05       Impact factor: 0.975
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