Literature DB >> 8371832

Ganglioside composition changes in spongiform encephalopathies: analyses of 263K scrapie-infected hamster brains.

A Di Martino1, J Safar, L Callegaro, N Salem, C J Gibbs.   

Abstract

Ganglioside composition in brains of terminally ill LVG/LAK golden Syrian hamsters infected with the 263K strain of the scrapie agent was analyzed. Results were compared to those obtained from noninfected animals matched by age, sex, and strain. Gangliosides extracted from scrapie-infected animals showed little change in major components, while an increased number of new alkali-labile species appeared. Additionally, the animal strain employed demonstrated a significant polymorphism in brain ganglioside composition. No significant changes in incubation time, clinical development or pathologic features of scrapie were associated with this polymorphism.

Entities:  

Mesh：

Substances：

Year:  1993        PMID： 8371832     DOI： 10.1007/bf00998276

Source DB:  PubMed          Journal:  Neurochem Res        ISSN： 0364-3190            Impact factor:   3.996


  20 in total

1.  Quantitative estimation of sialic acids. II. A colorimetric resorcinol-hydrochloric acid method.

Authors:  L SVENNERHOLM
Journal:  Biochim Biophys Acta       Date:  1957-06

2.  Genetic polymorphism of ganglioside expression in mouse organs.

Authors:  K Nakamura; Y Hashimoto; T Yamakawa; A Suzuki
Journal:  J Biochem       Date:  1988-01       Impact factor: 3.387

3.  Purification of non-infectious ganglioside preparations from scrapie-infected brain tissue.

Authors:  A Di Martino; J Safar; M Ceroni; C J Gibbs
Journal:  Arch Virol       Date:  1992       Impact factor: 2.574

4.  Densitometric quantification of brain gangliosides separated by two-dimensional thin layer chromatography.

Authors:  V Chigorno; S Sonnino; R Ghidoni; G Tettamanti
Journal:  Neurochem Int       Date:  1982       Impact factor: 3.921

Review 5.  Gangliosides: structure, isolation, and analysis.

Authors:  R W Ledeen; R K Yu
Journal:  Methods Enzymol       Date:  1982       Impact factor: 1.600

6.  Ganglioside alterations in guinea pig brains at end stages of experimental Creutzfeldt-Jakob disease.

Authors:  R K Yu; E E Manuelidis
Journal:  J Neurol Sci       Date:  1978-01       Impact factor: 3.181

7.  PREPARATION OF FATTY ACID METHYL ESTERS AND DIMETHYLACETALS FROM LIPIDS WITH BORON FLUORIDE--METHANOL.

Authors:  W R MORRISON; L M SMITH
Journal:  J Lipid Res       Date:  1964-10       Impact factor: 5.922

8.  Evidence for nonrandom distribution of GD1a ganglioside in rabbit brain microsomal membranes.

Authors:  P Palestini; M Masserini; A Fiorilli; E Calappi; G Tettamanti
Journal:  J Neurochem       Date:  1991-09       Impact factor: 5.372

9.  A solvent partition method for microscale ganglioside purification.

Authors:  S Ladisch; B Gillard
Journal:  Anal Biochem       Date:  1985-04       Impact factor: 3.365

10.  Alterations in brain gangliosides and other lipids of patients with Creutzfeldt-Jakob disease and subacute sclerosing panencephalitis (SSPE).

Authors:  S Ando; Y Toyoda; Y Nagai; F Ikuta
Journal:  Jpn J Exp Med       Date:  1984-12
View more
  3 in total

Review 1.  Brain pathology in Niemann Pick disease type A: insights from the acid sphingomyelinase knockout mice.

Authors:  Maria Dolores Ledesma; Alessandro Prinetti; Sandro Sonnino; Edward H Schuchman
Journal:  J Neurochem       Date:  2011-01-07       Impact factor: 5.372

Review 2.  Deregulated sphingolipid metabolism and membrane organization in neurodegenerative disorders.

Authors:  Marco Piccinini; Federica Scandroglio; Simona Prioni; Barbara Buccinnà; Nicoletta Loberto; Massimo Aureli; Vanna Chigorno; Elisa Lupino; Giovanni DeMarco; Annarosa Lomartire; Maria Teresa Rinaudo; Sandro Sonnino; Alessandro Prinetti
Journal:  Mol Neurobiol       Date:  2010-02-03       Impact factor: 5.590

3.  Increased Expression of Simple Ganglioside Species GM2 and GM3 Detected by MALDI Imaging Mass Spectrometry in a Combined Rat Model of Aβ Toxicity and Stroke.

Authors:  Sarah Caughlin; Jeffrey D Hepburn; Dae Hee Park; Kristina Jurcic; Ken K-C Yeung; David F Cechetto; Shawn N Whitehead
Journal:  PLoS One       Date:  2015-06-18       Impact factor: 3.240
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.