Literature DB >> 8371547

GC/MS identification of tetramine in samples from human alimentary intoxication and evaluation of artificial carbonic kidneys for the treatment of the victims.

F Y Guan1, Y T Liu, Y Luo, X Y Hu, F Liu, Q Y Li, Z W Kang.   

Abstract

One day in July 1991, 78 people became victims of accidental alimentary intoxication in a factory in Hebei Province, China. Related samples, including rodenticide bait, the artificial carbonic kidneys used for the treatment of the victims, and the victims' blood, were analyzed by GC/MS. Tetramine [80-12-6], a highly toxic rodenticide, was identified as the toxicant. The effectiveness of artificial carbonic kidneys was evaluated. The analytical results revealed that detoxification of the patients was effective 48 hours after intoxication by percolating their blood through artificial carbonic kidneys.

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Year:  1993        PMID: 8371547     DOI: 10.1093/jat/17.4.199

Source DB:  PubMed          Journal:  J Anal Toxicol        ISSN: 0146-4760            Impact factor:   3.367


  6 in total

1.  Behavioral assessment of NIH Swiss mice acutely intoxicated with tetramethylenedisulfotetramine.

Authors:  Brenna M Flannery; Jill L Silverman; Donald A Bruun; Kyle R Puhger; Mark R McCoy; Bruce D Hammock; Jacqueline N Crawley; Pamela J Lein
Journal:  Neurotoxicol Teratol       Date:  2014-11-08       Impact factor: 3.763

2.  Characterization of seizures induced by acute and repeated exposure to tetramethylenedisulfotetramine.

Authors:  Dorota Zolkowska; Christopher N Banks; Ashish Dhir; Bora Inceoglu; James R Sanborn; Mark R McCoy; Donald A Bruun; Bruce D Hammock; Pamela J Lein; Michael A Rogawski
Journal:  J Pharmacol Exp Ther       Date:  2012-02-10       Impact factor: 4.030

3.  Tetramethylenedisulfotetramine alters Ca²⁺ dynamics in cultured hippocampal neurons: mitigation by NMDA receptor blockade and GABA(A) receptor-positive modulation.

Authors:  Zhengyu Cao; Bruce D Hammock; Mark McCoy; Michael A Rogawski; Pamela J Lein; Isaac N Pessah
Journal:  Toxicol Sci       Date:  2012-08-13       Impact factor: 4.849

4.  GABAA receptor subtype selectivity of the proconvulsant rodenticide TETS.

Authors:  Brandon Pressly; Hai M Nguyen; Heike Wulff
Journal:  Arch Toxicol       Date:  2017-10-16       Impact factor: 5.153

Review 5.  Tetramethylenedisulfotetramine: A Health Risk Compound and a Potential Chemical Warfare Agent.

Authors:  Jiří Patocka; Tanos C C Franca; Qinghua Wu; Kamil Kuca
Journal:  Toxics       Date:  2018-08-22

6.  Strain differences in the extent of brain injury in mice after tetramethylenedisulfotetramine-induced status epilepticus.

Authors:  Jonas J Calsbeek; Eduardo A González; Casey A Boosalis; Dorota Zolkowska; Donald A Bruun; Douglas J Rowland; Naomi H Saito; Danielle J Harvey; Abhijit J Chaudhari; Michael A Rogawski; Joel R Garbow; Pamela J Lein
Journal:  Neurotoxicology       Date:  2021-08-31       Impact factor: 4.294

  6 in total

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