| Literature DB >> 8371051 |
A T Lesnyak1, G Sonnenfeld, M P Rykova, D O Meshkov, A Mastro, I Konstantinova.
Abstract
Over the past two decades, it has become apparent that changes in immune parameters occur in cosmonauts and astronauts after spaceflight. Therefore, interest has been generated in the use of animal surrogates to better understand the nature and extent of these changes, the mechanism of these changes, and to allow the possible development of countermeasures. Among the changes noted in animals after spaceflight are alterations in lymphocytic blastogenesis, cytokine function, natural killer cell activity, and colony-stimulating factors. The nature and significance of spaceflight-induced changes in immune responses will be the focus of this review.Entities:
Keywords: NASA Discipline Number 00-00; NASA Discipline Number 18-10; NASA Discipline Regulatory Physiology; NASA Program Flight; NASA Program Space Physiology and Countermeasures; Non-NASA Center
Mesh：
Year: 1993 PMID： 8371051 DOI： 10.1002/jlb.54.3.214
Source DB: PubMed Journal: J Leukoc Biol ISSN： 0741-5400 Impact factor: 4.962